Genezen

Genezen

Sr. Scientist, Analytical Development

Lexington, MA · Senior

Work authorization required$120k-$150kDetected 23 days ago
Clinical TrialsGMPqPCRCRISPRFlow CytometryMolecular BiologyResearchExperimental DesignMass SpectrometryProtein AnalysisLeadershipCommunicationWritingAdaptability

About the role

  • The position requires expertise in potency and other cell based assays, ddPCR/qPCR, and ELISA.
  • Considerable expertise with technical writing of protocols, SOPs, and technical reports.
  • Experience in HPLC based methodology development and establishment including with the use of CAD and MALS detectors for use in the characterization of AAV vectors

Responsibilities

  • Expert in method qualification/validation experimental design per ICH guidelines
  • Expert in ddPCR/qPCR from primer design and optimization to implementation
  • Maintain familiarity with other current analytical and bioassay methods, including Flow cytometry
  • Maintain familiarity with current equipment used in Analytics lab
  • Qualify/validate analytical methods to support cGMP testing
  • Support the establishment of electronic record keeping systems for site; e.g. LIMS or ELN

Requirements

  • 5-6 years experience post graduation (with PhD), 6-8 years experience post graduation (with Masters), 8-12 years experience post graduation (with Bachelors)
  • Expertise in molecular biology in the characterization of AAV particles and associated impurities.
  • Experience with documentation and reporting of results using electronic lab notebooks
  • Experience with biophysical characterization methods including HPLC, LC-MS, CE-SDS etc.
  • Direct line management experience is required.
  • Experience with AAV assay development is critical
  • Experience with specification setting for complex biologics

Skills

  • BS in scientific/technical discipline
  • People training and leadership skills
  • Ability to maintain multiple projects and timelines
  • Excellent verbal and written communication skills
  • Extremely high levels of initiative, adaptability, tenacity and troubleshooting skills
  • Essential/Desired

Compensation

  • The annual salary range for the Senior Scientist is $120,000-$150,000.
  • Frequently required to work in BSL2 environment with personal protective equipment/aseptic gowning
  • Occasionally exposed to moving mechanical parts, toxic or caustic chemicals, hazardous waste, and similar hazards associated with pharmaceutical lab facilities
  • Frequently required to stand; sit; use hands to finger, handle, or feel; reach with hands and arms
  • Occasionally required to walk; climb or balance; and stoop, kneel, crouch, or crawl
  • Frequently lift and/or move up to 10 pounds

Benefits

  • Frequently utilize close vision and the ability to adjust focus
  • Paid vacation days, amount based on tenure
  • 10 observed holidays + 2 floating holiday + 1 volunteer day
  • We are committed to scientific excellence, staying current with industry developments, making data-driven decisions, and pursuing innovation to advance healthcare.
  • We are committed to overcoming challenges, learning from failures, and persistently striving for success.
  • Choice of several healthcare plans
  • FSA and HSA programs
  • Dental & vision care

Company info

  • The field of gene therapy is growing rapidly and Genezen is here to meet the exacting needs of our clients.
  • We provide process development, produce GMP viral vectors, and provide cell transduction for gene and cell therapy clinical trials and are proud to be a part of the process that leads to new cures.
  • Many people have worked in environments where you feel like just another nameless part of an enormous machine.
  • Genezen is different.
  • We want our employees to be innovative, collaborative problem solvers who are dedicated to meeting the challenges of working at a fast-growing company.
  • We are dedicated to empowering our employees to be their best and making Genezen a rewarding place to work.
  • Every employee contributes to the success of the company and you can be part of that team.
  • We are dedicated to delivering quality results and upholding ethical principals.

Visa & Work Authorization

  • en is interested in every qualified candidate who is eligible to work in the United States; however, we are not able to sponsor visas
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This listing is sourced directly from Genezen's careers page and normalized into a canonical job model.