Kiniksapharmaceuticals

Senior Director, GI & Inflammatory Disease Research

Lexington, MA · Director

Sponsorship not specified$294k-$311kDetected 6 days ago

Clinical TrialsClinical ResearchPharmacologyFDA RegulatoryMolecular BiologyResearchAnimal StudiesLeadershipPublic Speaking

About the role

Grounded in rigorous science and bold innovation, the company fosters a highly collaborative, patient‑first culture led by accomplished life sciences leaders.
At Kiniksa, talented individuals are trusted and empowered to make a real impact-shaping the future of medicine while improving the lives of patients who need it most.
This role will be particularly valuable for candidates with deep expertise in protease biology, inflammation, immunology, and GI diseases.

Lead disease biology strategy for discovery and preclinical-stage programs, with emphasis on protease, immune-mediated, and GI diseases.
Develop mechanistic understanding of disease pathways and translate biological insights into therapeutic opportunities.
Partner with DMPK, toxicology, bioanalytics, and clinical pharmacology teams to establish robust development strategies.
Support first-in-human, dose-escalation, and proof-of-concept studies through integration of nonclinical and emerging clinical data.
Lead multidisciplinary project teams and influence portfolio strategy. Collaborate with Clinical Development, CMC, Regulatory, and Program Leadership to ensure seamless translation from research to clinical development.
Present program recommendations and scientific strategy to executive leadership, governance committees, partners, and external stakeholders.
Mentor and develop a high-performing disease biology team.
Strong strategic thinking and decision-making skills to support portfolio and program advancement.

15+ years of biotechnology and/or pharmaceutical industry experience, including significant leadership responsibilities.
Extensive experience supporting development of biologic therapeutics.
Proven track record of scientific publications, external presentations, patents, and/or successful development milestones.
Experience working in highly matrixed environments and leading cross-functional teams.

Experience in inflammatory, autoimmune, or GI disease biology is highly preferred.

Strong expertise in protease biology, immunology, and GI disease biology.
Experience advancing biologic therapeutics from discovery through clinical development.
Ability to translate complex scientific findings into development and translational strategies.
Proven leadership of cross-functional teams in a matrixed drug development environment.

Compensation decisions are based on objective criteria including role responsibilities, experience/qualifications, internal equity, geographic location, and external market benchmarks.
decisions are based on objective criteria including role responsibilities, experience/qualifications, internal equity, geographic location, and external market benchmarks.

This listing is sourced directly from Kiniksapharmaceuticals's careers page and normalized into a canonical job model.