Biogen
Senior Scientist, Immunology
San Francisco, CA · Senior
Sponsorship not specified$123k-$164kDetected 6 days ago
Business DevelopmentPharmacologyBioinformaticsqPCRFlow CytometryMolecular BiologyCell CultureResearchExperimental DesignProtein AnalysisAnimal StudiesCommunicationCollaborationProblem SolvingPublic Speaking
About the role
- We are seeking a highly motivated and accomplished Senior Scientist with drug discovery experience in diseases with an inflammatory etiology to join our growing Immunology Research Unit in South San Francisco.
- This role offers an exciting opportunity to work in a dynamic, multidisciplinary environment at the nexus of basic research, translational science, and therapeutic innovation.
Responsibilities
- Conceive, design, and execute innovative in vitro and in vivo studies to investigate mechanisms underlying inflammatory and autoimmune diseases.
- Identify and validate novel drug targets, biomarkers, and immune pathways relevant to immune-mediated disorders.
- Generate high-quality, decision-enabling data to support target validation, lead optimization, biomarker discovery, and translational research for priority immunology programs.
- Develop, optimize, and implement immunological assays, including cellular, biochemical, and functional assays using primary human or murine immune cells, patient-derived samples, and disease-relevant model systems.
- Collaborate cross-functionally with colleagues in pharmacology, medicinal chemistry/synthetic medicine, protein engineering, computational biology, translational sciences, and clinical development to advance discovery and development programs.
- Support evaluation of external scientific opportunities, including mechanistic assessments, data review, and scientific due diligence in partnership with senior scientific leaders, business development, and corporate strategy teams, as appropriate.
Requirements
- You are passionate about advancing immunology through rigorous science, creative problem-solving, and collaborative drug discovery.
- Candidates must be within commutable distance or able to self-relocate to be considered.
- Strong expertise in immune cell biology, including innate and adaptive immunity, cell signaling, cytokine biology, and immunological assay development.
- Experience isolating, culturing, and profiling primary murine or human immune cells and/or patient-derived samples.
- Experience with in vivo and ex vivo disease models of inflammation and/or autoimmunity.
- Strong analytical, problem-solving, and communication skills, including the ability to translate complex scientific data into clear, program-relevant insights.
- Collaborative mindset with strong interpersonal skills and a demonstrated ability to work across scientific disciplines.
- PhD preferred, or MS/BS with significant relevant experience, in Immunology, Cellular and Molecular Biology, Pharmacology, or a related scientific field with 2+ years of relevant industry experience (MS with 6+, BS with 8+) in biotech/pharma drug discovery or translational research, preferably in inflammatory and autoimmune disease biology.
- Hands-on experience with relevant techniques such as biochemical and cellular assay development, tissue culture, flow cytometry, ELISA/MSD, RNA and protein analysis, qPCR/RNA-seq, Jess or related protein analysis platforms, and/or functional genomics approaches.
- Ability to manage multiple priorities, work independently, and contribute effectively in team-based program settings.
Nice to have
- Prior experience in biotech/pharma drug discovery or translational research, particularly in immunology, inflammation, or autoimmune disease.
- Experience working with small molecules, biologics, and/or cell-based therapeutic approaches in drug discovery and development.
- Strong technical expertise in multiparametric flow cytometry, including high-dimensional panels, e.g., 15+ colors.
- Experience with multiomics analyses, including genomic, transcriptomic, proteomic, or integrated biomarker datasets.
- Exposure to external opportunity assessment, scientific diligence, or competitive landscape evaluation is a plus.
- Job Level: Management
- Additional Information
- The base compensation range for this role is: $123,000.00-$164,000.00
Compensation
- Tuition reimbursement of up to $10,000 per calendar year
Benefits
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Paid Maternity and Parental Leave benefit
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Employee stock purchase plan
- Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.
Company info
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 401(k) program participation with company matched contributions
- We are a global team with a commitment to excellence, and a pioneering spirit.
- As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact.
This listing is sourced directly from Biogen's careers page and normalized into a canonical job model.