Nurix Therapeutics
Senior Scientist, Medicinal Chemistry
The Woodlands, Texas · Senior
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DOL prevailing wage, 2026-27 wage year · Chemists (19-2031) · Houston-Pasadena-The Woodlands, TX. Wage level is derived by USCIS from the offered wage, occupation and worksite; the occupation shown is inferred from the job title.
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About the role
- Provide scientific guidance, coaching, and mentorship to other scientists
- Communicate scientific rationale, data, and recommendations clearly to project teams, leadership, and broader scientific audiences
Responsibilities
- Design novel chemical entities and medicinal chemistry strategies, applying structure-based drug design to optimize potency, selectivity, physicochemical, ADME/PK, safety, and in vivo efficacy
- Design synthetic strategies for complex molecules using modern and creative synthetic methods
- Develop innovative concepts that establish new directions and address complex challenges, drawing on emerging literature, patents, and competitive intelligence to inform compound design and strategy
- Lead chemistry workstreams within multidisciplinary teams, independently manage priorities and external collaborations, and contribute to project strategy and key scientific decisions
- Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases.
Requirements
- BS or MS with 14+ years of relevant experience, or PhD with 8+ years of relevant experience
- Ability to establish new chemical, scientific, or strategic directions from experimental data, structural insights, literature, patents, and emerging science, and to influence decisions within multidisciplinary teams
Skills
- Excellent written and verbal communication skills for multidisciplinary teams, senior leadership, and external audiences
- Strong team orientation; highly collaborative
- Solutions and results-oriented focus
- Hands-on approach; resourceful and open to diverse points of view
Compensation
- $147,500 - $157,500
This listing is sourced directly from Nurix Therapeutics's careers page and normalized into a canonical job model.