Pfizer

Pfizer

Senior Research Scientist, High Content Imaging and Cellular Assay Pharmacology

United States - Connecticut - Groton · Senior

Sponsorship not specified$94k-$156kDetected 9 days ago
AlgorithmsData AnalysisAccessibilityRecruitingClinical TrialsPharmacologyBioinformaticsCRISPRFlow CytometryMolecular BiologyResearchExperimental DesignLeadershipCommunicationCollaborationProblem Solving

About the role

  • Your efforts will accelerate the delivery of best-in-class medicines to patients globally, fulfilling Pfizer's commitment to making a meaningful difference in healthcare.
  • The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Responsibilities

  • Independently develop, optimize, and troubleshoot assays focusing on but not limited to high-content imaging and flow cytometry assays.
  • Execute routine screens and mechanism-of-action studies using high-content imaging and/or flow cytometry as well as molecular approaches to support programs across target validation, small-molecule identification and optimization, and clinical candidate selection.
  • Independently analyze assay data, including applying advanced image-analysis methods to develop and optimize analysis algorithms; perform quality control, process screening data, and communicate results clearly.
  • Partner with project team members and DBP colleagues to design and execute studies that address project needs, interpret data to answer key questions, and help guide project direction when needed.

Requirements

  • Technical expertise: Hands-on experience with high-content imaging and flow cytometry instrumentation, with familiarity in advanced image-analysis methods and software.
  • Cell models and characterization: Hands- on experience with physiologically relevant cell models (primary cells, iPSC-derived models).
  • Familiarity with cell characterization methods and gene delivery systems.
  • Scientific foundation: Broad and applied knowledge of cellular and molecular biology, with the ability to connect biological questions to appropriate assay strategies.
  • Problem solving: Strong willingness and ability to troubleshoot, solve problems, and overcome technical or scientific challenges.
  • Collaboration: Strong interpersonal and collaboration skills, with the ability to work efficiently and productively in team-based settings.
  • Hands-on experience with high-content imaging and flow cytometry instrumentation, with familiarity in advanced image-analysis methods and software.
  • Hands- on experience with physiologically relevant cell models (primary cells, iPSC-derived models).
  • Broad and applied knowledge of cellular and molecular biology, with the ability to connect biological questions to appropriate assay strategies.
  • Demonstrated ability to acquire relevant disease area biology knowledge efficiently and apply this to a broad range of target classes.
  • Must Have
  • Education: PhD in Molecular Biology, Pharmacology, Cell Biology, or a related discipline with 1 to 3 years' experience in cellular assay development
  • Cell models and characterization: Hands- on experience with physiologically relevant cell models (primary cells, iPSC-derived models). Familiarity with cell characterization methods and gene delivery systems.
  • Learning agility: Demonstrated ability to acquire relevant disease area biology knowledge efficiently and apply this to a broad range of target classes.
  • Communication: Demonstration of excellent verbal and written communication skills.

Nice to have

  • Experience across therapeutic areas such as Internal Medicine, Immunology & Inflammation, or Oncology.
  • Exposure to functional genomics approaches, including RNA-seq and CRISPR-based methods.
  • May periodically be asked to travel to the Pfizer Cambridge, MA site to meet project team members and to attend appropriate meetings and conferences.
  • Must comply with all laboratory safety practices.
  • Other Job Details
  • Relocation assistance may be available based on business needs and/or eligibility.
  • Candidates must be authorized to be employed in the U.S. by any employer.
  • U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Skills

  • Use Your Power for Purpose
  • What You Will Achieve
  • Demonstration of excellent verbal and written communication skills.

Compensation

  • The annual base salary for this position ranges from $93,600.00 to $156,000.00.

Benefits

  • Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com).
  • Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.
  • These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure.
  • In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program.
  • We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments.
  • Pfizer compensation structures and benefit packages are aligned based on the location of hire.

Equal opportunity

  • This is to be used solely for accommodation requests with respect to the accessibility of our website, online

Visa & Work Authorization

  • U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
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