St. Jude Children’s Research Hospital
Staff Software Engineer / Machine Learning Engineer - Radiology
Memphis, TN · Staff+
Sponsorship not specified$104k-$186kDetected 20 days ago
PythonAlgorithmsCode ReviewGitMachine LearningDeep LearningTensorFlowPyTorchData ScienceNLPLLMsCybersecurityPenetration TestingFDA RegulatoryMedical DevicesRadiologyResearchCollaboration
About the role
- This position sits at the center of a well-resourced, data-rich research environment with established infrastructure for multi-institutional data aggregation, curation, and large-scale annotation.
- Jude Children's Hospital has incredible high-performance computing resources.
- This role offers a unique combination of academic productivity (authorship opportunities) and real-world impact through translation into clinical practice.
Responsibilities
- Develop, train, and validate state-of-the-art ML/DL models for segmentation, quantification, and detection across CT, MRI, and X-ray
- Design and implement 2D and 3D model architectures (CNNs, transformer-based, and foundational models)
- Build scalable pipelines for data preprocessing, model training, evaluation, and deployment
- Develop quantitative imaging methods (e.g., volumetrics, density measurements, biomarker extraction)
- Collaborate with radiologists and engineering teams to define clinically meaningful outputs
- Work collaboratively with regulatory and quality experts to support FDA 510(k) and De Novo submissions, including providing technical documentation and validation evidence
Requirements
- Bachelor's degree with 5+ years of experience required.
- Bachelor's degree in computer science, data science, information science, business, or related field.
- Experience Exception: Master's degree with 3+ years of experience.
- Experience with programming languages, databases, and software development lifecycle
Nice to have
- 3+ years of experience developing ML/DL models for image analysis
- Demonstrated experience with segmentation, detection, and/or quantitative imaging algorithms (2D and/or 3D)
- Experience with modern architectures (U-Net variants, detection frameworks, transformers, or foundational models)
- Strong understanding of evaluation metrics (Dice, IoU, ROC/AUC, sensitivity/specificity)
- Experience with version control and collaborative development (e.g., Git)
- Demonstrated ability to produce clear, structured technical documentation
- Experience using modern LLM-based coding assistants (e.g., Claude, Codex, or similar) to enhance development workflows
- Experience collaborating with regulatory, quality, or cybersecurity teams
Skills
- Leverage curated, multi-institutional datasets to ensure model generalizability and robustness
- Produce regulatory-grade documentation for datasets, model development, validation, and performance
- Ensure reproducibility and traceability of experiments (data, model, and code versioning)
- Utilize modern AI-assisted development tools (e.g., LLM-based coding agents) to accelerate development and improve code quality
- Participate in team-based development practices (code reviews, Git, testing frameworks)
- Support manuscripts, grants, and technical reporting
Compensation
- In recognition of certain U.S. state and municipal pay transparency laws, St.
- Jude is including a reasonable estimate of the compensation range for this role.
- It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case.
- A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Staff Software Engineer / Machine Learning Engineer - Radiology.
- This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs.
Benefits
- Minimum Education and/or Training:
- Explore our exceptional benefits!
Equal opportunity
- Jude is an Equal Opportunity Employer
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