AstraZeneca
Senior Automation Engineer, Laboratory Automation – Analytical Sciences
US – Santa Monica Colorado Avenue – CA · Senior
Sponsorship not specified$103k-$155kDetected 6 days ago
PythonC++Data AnalysisStakeholder ManagementAutoCADFusion 360Mechanical DesignElectrical EngineeringGMPFlow CytometryCell CultureCommunicationProblem Solving
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59Sponsors, lottery-bound
Cap-exempt (no lottery)0
Sponsors this role100
Entry-level history0
PERM / green-card track0
Lottery odds (Level III)83
Fits your clock70
Sponsors, but it's cap-subject — you still face the weighted lottery (~45% per draw at Level III). Good if you win; have a cap-exempt backup on your list.
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About the role
- This fully on-site role is based in Santa Monica, California.
- The role combines hands-on engineering with project execution and stakeholder management to improve assay robustness, workflow efficiency, and data quality for novel engineered cell therapy products.
- Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles.
Responsibilities
- Design, build, and implement automation solutions for cell-based, immunological, and genomic assays
- Program, test, and maintain Hamilton VANTAGE and other automated liquid-handling workstations
- Develop and optimize liquid-handling scripts for complex bioassay workflows
- Partner with scientists, engineers, and IT specialists to translate manual processes into robust automated workflows
- Troubleshoot, maintain, and continuously improve automated systems to ensure reliable performance
- Support the transfer of automated assay methods to Quality Control teams and external partners
- Create and maintain SOPs, user guides, and technical reports
- Experience developing integrated automation workflows using scheduling software such as HighRes Cellario
- 29-Oct-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees.
Requirements
- Bachelor's or master's degree in bioengineering, biotechnology, mechanical engineering, electrical engineering, or a related field of hands-on experience with laboratory automation systems
- Advanced expertise with Hamilton liquid-handling platforms and VENUS software
- Proficiency in Python, C++, or a similar programming language
- Experience with cell culture, immunological assays, and flow cytometry
- Knowledge of GMP requirements and experience in a regulated environment
- Demonstrated ability to proactively communicate progress, risks, decisions, and resource needs
- Ability to balance hands-on engineering with project execution, stakeholder alignment, and business priorities
Nice to have
- Knowledge of cell therapy development and manufacturing processes
- Familiarity with QbD principles
- Experience applying DoE approaches to method development
- Experience with data analysis and visualization tools such as Prism, JMP, or FlowJo
- Experience with computer-aided design tools such as AutoCAD or Fusion 360
- Experience using 3D printing for laboratory automation applications
- Experience with LIMS such as Benchling or Labguru, and their integration with laboratory automation schedulers
- In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics.
Compensation
- The annual base pay (or hourly rate of compensation) for this position ranges from $103,286.40 to $154,929.60.
Benefits
- offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Company info
- We are seeking an accomplished Senior Automation Engineer to join the Laboratory Automation team within Analytical Sciences.
Equal opportunity
- If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
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This listing is sourced directly from AstraZeneca's careers page and normalized into a canonical job model.