Novartis

Novartis

Director / Executive Director, Modeling & Simulation (Dual Level Posting)

Cambridge (USA) · Director

Sponsorship not specifiedDetected 71 days ago
AlgorithmsData EngineeringPerformance ManagementClinical TrialsPharmacologyResearchAnimal StudiesLeadershipCommunicationCollaborationMentoring

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About the role

  • Define and execute disease modelling strategies aligned with portfolio priorities, ensuring models address key decision questions across discovery and development.
  • Novartis is a leader in mechanistic modelling and simulation.
  • This role reports to the Global Head of Modeling & Simulation (M&S) within Translational Medicine in Biomedical Research.

Responsibilities

  • Lead and develop a high-performing team focused on disease modelling, including recruitment, coaching, performance management, and talent development.
  • Develop and apply mechanistic disease models (e.g., QSP, systems biology, integrative PK/PD-disease frameworks) to understand disease progression, variability, and response to intervention.
  • Drive portfolio-level impact, including modelling to support target selection, indication prioritisation, competitive differentiation, and probability of technical success.
  • Collaborate with PKS and TM leadership to shape scientific priorities and ensure alignment with broader M&S and organisational strategy.
  • Lead or contribute to cross-functional initiatives that advance modelling capabilities, including adoption of innovative approaches (e.g., AI-enabled methods, digital twins where relevant).
  • Drive scientific excellence and continuous improvement, ensuring use of state-of-the-art methodologies and strengthening disease modelling capabilities across the organisation.
  • We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Requirements

  • Extensive leadership experience required for Executive Director level (8+ years).
  • Strong understanding of drug discovery and development, and how modelling informs key transitions from discovery to clinical development.
  • The final level & title of the offer role would be determined by the hiring team based on the skills, experience & capabilities required to perform the role at the level the role has been offered

Skills

  • Algorithms, Clinical Trials, Data Engineering, Innovation, People Management, Simulation Software, Strategy Execution, Waterfall Model

Compensation

  • Director: $176,400 and $327,600 per year.
  • $225,400 and $418,600 per year.
  • The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically.
  • Novartis may change the published salary range based on company and market factors.
  • Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
  • $176,400.00 - $327,600.00

Benefits

  • US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits.
  • In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
  • To learn more about the culture, rewards and benefits we offer our people click here

Equal opportunity

  • The Novartis Group of Companies are Equal Opportunity Employers.
  • The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities.
  • EEO Statement:
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This listing is sourced directly from Novartis's careers page and normalized into a canonical job model.