Radical Numerics

Radical Numerics

Member of Technical Staff, Computational Biology

San Francisco · Staff+

Work authorization required$26k-$42kDetected 166 days ago
PythonDistributed SystemsGitMachine LearningBioinformaticsCRISPRResearch

About the role

  • As a science-focused Member of Technical Staff, you will curate the multimodal biological datasets that power our models, analyze model behavior, and ensure our model outputs meet rigorous scientific standards.

Responsibilities

  • Build evaluation suites and benchmarks that stress-test generative biological models across modalities and tasks.
  • Partner with AI engineers to analyze model outputs, run ablations, and surface insights that guide future architecture and training improvements.
  • Clear communicator who can bridge scientific context with engineering teams and partner organizations.
  • You'll co-develop benchmarks, filters, and validation pipelines with engineering peers so biological world models remain trustworthy and actionable.

Requirements

  • PhD in genetics, computational biology, or a related field, OR demonstrated experience in biotech with a strong track record of impact over 3+ years.
  • Proven experience curating, harmonizing, and analyzing large biological datasets (e.g., genomics, single-cell, spatial, or imaging).
  • Ability to interrogate model outputs, debug unexpected behaviors, and translate findings into actionable recommendations.

Nice to have

  • Familiarity with generative model evaluation, red-teaming, or safety analysis in scientific domains.
  • Experience with statistical validation, quality control, or benchmarking for scientific or ML systems.
  • Contributions to shared analytics tooling or reproducible research pipelines.
  • Collaborative culture that values rigor, creativity, and cross-disciplinary partnership across AI labs, biotechs, hospital systems, and national research institutes.
  • It also prohibits unlawful discrimination based on the perception that anyone has any of those characteristics, or is associated with a person who has or is perceived as having any of those characteristics.
  • Radical Numerics participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S.

Compensation

  • Competitive compensation, comprehensive benefits, and support for continual learning.

Company info

  • Radical Numerics http://radicalnumerics.ai is an AI research lab building general biological intelligence. Our mission is to master the code of life, and our purpose is to reduce human suffering.
  • Our team created Evo, and started the field of generative genomics. Our work was featured on the cover of Science https://www.science.org/doi/10.1126/science.ado9336, and presented by our CEO on the main stage of TED2025 https://www.youtube.com/watch?v=EnbfoFUFm2s. Evo was used to create the first AI gene therapy tool CRISPR-Cas9, and the first AI whole genome https://www.biorxiv.org/content/10.1101/2025.09.12.675911v1 from scratch. Evo 2 https://www.nature.com/articles/s41586-026-10176-5, featured in Nature, is the largest fully open source AI project across any domain.
  • Radical Numerics is bringing the rigor of distributed systems, model architecture, and numerics research to the challenges of biology. We've redesigned the foundation model training stack to turn the world's raw scientific data (e.g. biological sequences, experiments, and physical processes), into intelligible, generative models that can expand and accelerate what humanity can understand, design, and cure.
  • The same generative breakthroughs that enable life-saving cures also lowers the barrier to creating engineered threats and AI-generated bioweapons. We believe these forces are inseparable. Radical Numerics was founded to develop both the power to design and the responsibility to defend.
  • Radical Numerics http://radicalnumerics.ai is an AI research lab building general biological intelligence.
  • Our mission is to master the code of life, and our purpose is to reduce human suffering.
  • Our team created Evo, and started the field of generative genomics.
  • Our work was featured on the cover of Science https://www.science.org/doi/10.1126/science.ado9336, and presented by our CEO on the main stage of TED2025 https://www.youtube.com/watch?v=EnbfoFUFm2s.
  • Evo was used to create the first AI gene therapy tool CRISPR-Cas9, and the first AI whole genome https://www.biorxiv.org/content/10.1101/2025.09.12.675911v1 from scratch.
  • Evo 2 https://www.nature.com/articles/s41586-026-10176-5, featured in Nature, is the largest fully open source AI project across any domain.
  • Radical Numerics is bringing the rigor of distributed systems, model architecture, and numerics research to the challenges of biology.
  • We've redesigned the foundation model training stack to turn the world's raw scientific data (e.g. biological sequences, experiments, and physical processes), into intelligible, generative models that can expand and accelerate what humanity can understand, design, and cure.
  • The same generative breakthroughs that enable life-saving cures also lowers the barrier to creating engineered threats and AI-generated bioweapons.
  • We believe these forces are inseparable.
  • Radical Numerics was founded to develop both the power to design and the responsibility to defend.

Visa & Work Authorization

  • Radical Numerics participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S.
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