Elanco

Elanco

Senior Research Scientist - Medicinal Chemist

Indianapolis, IN · Senior

Sponsorship not specifiedDetected 29 days ago
Machine LearningPharmacologyResearchExperimental DesignAnimal Studies

About the role

  • Senior Research Scientist - Medicinal Chemist
  • You will apply your expertise to advance therapeutic programs by guiding Structure-Activity Relationship (SAR) studies and collaborating closely with a global, cross-functional team of scientists.
  • Leveraging modern technologies like AI/ML and DNA-Encoded Libraries, you will help solve complex chemical challenges and make a meaningful impact on our discovery portfolio.

Responsibilities

  • Guide the design of novel small molecules and propel Structure-Activity Relationship (SAR) studies by integrating biological, pharmacological, and ADME/PK data into iterative design strategies.
  • Manage and coordinate the synthesis, purification, and characterization of compounds with external Contract Research Organizations (CROs) and internal partners to ensure timely project delivery.
  • Apply advanced drug discovery technologies, including DNA-Encoded Libraries (DEL) and AI/ML-enabled molecular design tools, to accelerate hit identification and lead optimization.
  • Collaborate as a key member of multidisciplinary project teams, partnering with scientists in Biology, Pharmacology, DMPK, Toxicology, and Computational Sciences to advance discovery programs.
  • Maintain high standards of experimental design, data integrity, and scientific documentation to support data-driven judgments across the discovery portfolio.
  • Elanco may use automated tools, including AI, to support parts of our recruitment process, such as reviewing applications against job‑related criteria and/or transferrable skills.

Requirements

  • What You Need to Succeed (minimum qualifications):

Skills

  • What will give you a competitive edge (preferred qualifications):
  • Postdoctoral experience.
  • A track record of contributing to small-molecule programs that have advanced into preclinical development.
  • Prior experience in the animal health industry.
  • Expertise in peptide chemistry and optimization.

Compensation

  • Annual bonus offering

Benefits

  • Two weeklong shutdowns (mid-summer and year-end) in the US (in addition to PTO)
  • 8-week parental leave
  • Annual bonus offering
  • Flexible work arrangements
  • Education: PhD in Medicinal Chemistry, Organic Chemistry, or a related discipline.

Company info

  • At Elanco we are dedicated to building a diverse and inclusive work environment.

This listing is sourced directly from Elanco's careers page and normalized into a canonical job model.