Nurix Therapeutics

Nurix Therapeutics

Research Associate II, Bioanalytical/In Vitro ADME/DMPK

Brisbane, CA · Mid

Sponsorship not specified$93k-$107kDetected 17 days ago
Patient CareResearchMass SpectrometryAnimal StudiesCommunication

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odds of building a lasting career here

47Sponsors, lottery-bound
Cap-exempt (no lottery)0
Sponsors this role80
Entry-level history0
PERM / green-card track0
Lottery odds (Level II)66
Fits your clock70

Sponsors, but it's cap-subject — you still face the weighted lottery (~30% per draw at Level II). Good if you win; have a cap-exempt backup on your list.

Lottery odds assume a STEM candidate.

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Files H-1B transfers

2 transfer filings in the last year, covering 2 workers. Median labor-condition decision: 8 days. An employer that already files transfers is one that can take over an existing H-1B.

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About the role

  • Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine's next chapter with a new script to outmatch disease.
  • Position Nurix Therapeutics is searching for a motivated Research Associate II to join our Bioanalytical-In Vitro DMPK team.
  • The primary responsibilities will be to conduct bioanalysis for in vivo samples and to conduct in vitro experiments.

Responsibilities

  • Provide bioanalytical support for in-house PK, non-GLP safety TK
  • Conduct bioanalytical method development and qualification to support drug, metabolite and biomarker analysis
  • Independently develop LC-MS/MS methods to quantitate small molecules in in vitro and in vivo samples
  • Perform metabolic identification (MetID) using LC-QTOF MS/MS, including accurate mass analysis, fragment interpretation and biotransformation pathway assignment
  • Independently operate, troubleshoot and maintain LC-MS/MS systems
  • Participate in multidisciplinary project teams and collaborate with other departments to understand bioanalytical needs for both PK and PD support
  • Manage projects conducted at CROs to ensure high quality bioanalytical data is delivered to meet project timelines
  • Maintain accurate and detailed scientific electronic laboratory notebooks
  • Perform all duties in keeping with the Company's core values, policies and all applicable regulations
  • Provide sample analysis to support PK, PK/PD, PK/efficacy, distribution, metabolism, and non-GLP toxicology studies

Requirements

  • BS or master's with 4 years' experience working in a discovery setting using LC-MS/MS within a pharmaceutical/biotechnology company
  • Broad experience in small molecule drug candidate bioanalytical assay development/sample analysis in different biological matrices using LC-MS/MS
  • Experience with AB SCIEX mass spectrometry software
  • Experience with H/UPLC and mass spectrometry

Nice to have

  • Management experience with CROs for outsourcing BA activities is preferred

Compensation

  • Salary Range 93K - 107K

Company info

  • We are seeking a highly motivated research associate to characterize the in vitro and in vivo ADME of drug candidates.

This listing is sourced directly from Nurix Therapeutics's careers page and normalized into a canonical job model.