Cloverleaf Bio

Cloverleaf Bio

Scientist, RNA Biochemistry

New Haven, CT

Sponsorship not specifiedDetected 791 days ago
Data AnalysisBioinformaticsPCRqPCRMolecular BiologyNGSCell CultureResearchWestern BlottingCommunicationCollaborationProblem Solving

About the role

  • Our tRNAs target an underappreciated vulnerability of cancer: addiction to high levels of tRNA modifying enzymes.
  • Cloverleaf's approach to drugging tRNA modifying enzymes uses engineered "trojan horse" tRNAs to modulate translation in cancerous cells.
  • The programmability, potency, and specificity of our tRNAs gives us the potential to dramatically improve cancer treatment.

Requirements

  • Experience with standard molecular biology techniques, including but not limited to, RNA/DNA extraction, PCR, RT-PCR, qPCR, western blotting, etc.
  • Research experience in tRNA, RNA biology and/or RNA modifications field.
  • Experience with design/development RNA therapeutics and lipid nanoparticles.
  • Experience with mouse models of oncology.

Benefits

  • Benefits Competitive salary commensurate with experience and strong equity incentives.
  • Medical, dental, and vision coverage.

Company info

  • Cloverleaf Bio is an early-stage therapeutics company that is developing a new class of engineered tRNA therapeutics.
  • The Job We are seeking an experienced RNA Biochemist to join our team.
  • In this position, you will work in close conjunction with our founding team in the creation and development of a completely novel family of RNA therapeutics.
  • Your responsibilities will range from designing and performing both low and high-throughput RNA screening assays, generation of RNA sequencing libraries, performing mechanistic studies in cells on lead candidate RNAs, and diving into new disease areas beyond oncology.
  • About You Excited by the science.
  • We are excited by how science can improve the world and are looking for people who are too.
  • We wear many different hats and are looking for people who are willing to do whatever it takes to pitch in and get the job done.
  • Working in an early-stage startup can be hard.
  • Science is hard.
  • We are looking for people who have a demonstrated track record of sticking with complex problems for the long haul.
  • Cooperative.

This listing is sourced directly from Cloverleaf Bio's careers page and normalized into a canonical job model.