Twenty Twenty Therapeutics

Twenty Twenty Therapeutics

Senior Backend Software Engineer

Arlington, VA · Senior · Full-time

Sponsorship not specifiedDetected 121 days ago
GoBackend DevelopmentFull-Stack DevelopmentData StructuresAWSCloud PlatformsCI/CDGraphQLRESTMachine LearningCybersecurityTest Automation

About the role

  • ABOUT THE COMPANY America is under sustained cyber attack.
  • Our adversaries infiltrate our networks, steal our IP, and degrade the digital infrastructure that modern life runs on.
  • They've learned-correctly-that those attacks rarely produce consequences.

Responsibilities

  • Design and implement scalable backend services in Go that improve operator decision-making and response.
  • Build high-performance APIs that power customer-facing workflows and internal platform capabilities.
  • Model complex relationships in graph databases and optimize schemas and queries for speed and clarity.
  • Implement event-driven systems (e.g., with NATS) to process real-time operational data streams.
  • Develop and maintain automated tests to protect correctness, security, and performance as the system evolves.
  • Build and operate microservices deployed on AWS, with an eye toward resilience and cost-aware scaling.
  • Create and improve CI/CD pipelines that enable fast, secure delivery of new capabilities.
  • Partner with cyber operations experts to translate domain needs into robust product features.
  • Collaborate with frontend engineers on API contracts and data structures that are efficient and usable.
  • You collaborate well across disciplines, communicate clearly, and welcome direct feedback.

Requirements

  • You have strong proficiency with Go (Golang) and have shipped production services with it.
  • You have working knowledge of event-driven architectures and message queues/streaming systems.
  • You have experience with cloud infrastructure, ideally AWS, and understand cloud-native deployment patterns.
  • You have hands-on experience with containerization and microservices architectures.
  • You have a strong foundation in secure coding practices and can reason about security tradeoffs.
  • You have a bachelor's degree in Computer Science, Software Engineering, or a related field, or equivalent practical experience.

Nice to have

  • You've delivered software in defense, security, or other mission-critical environments.
  • You've built systems for analysts, operators, or high-tempo users where speed and reliability matter.
  • You've integrated AI/ML capabilities into production systems (inference, pipelines, or tooling).
  • You have experience with large-scale data processing and analytics workloads.
  • You've contributed meaningfully to open-source projects.
  • You've used observability tooling (metrics, tracing, logging) to debug and improve production systems.
  • Go (Golang), GraphQL/REST
  • Graph databases (Neo4j, AWS Neptune) and complex graph schemas

Benefits

  • We consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, veteran status, disability, or any other protected status.
  • Medical, dental, and vision plan options.
  • Life / AD&D, disability coverage options.
  • Paid parental leave for eligible full-time employees.
  • Paid holidays and flexible PTO.
  • HSA/FSA options, dependent care FSA.
  • Commuter benefits.
  • Building fitness center.
  • Desk setup stipend.
  • Benefits vary by location, role, and eligibility.

Company info

  • America is under sustained cyber attack.
  • Twenty was founded to change that, by making our adversaries think twice before they attack us.
  • Our vision is American and allied primacy in cyberspace-a future where they cannot contest us, deterrence is assured, and the free world remains secure.
  • Founded in 2024, Twenty Technologies (www.twenty.io http://www.twenty.io) industrializes offensive cyber operations for the U.S. and its allies.
  • Headquartered in Arlington, Virginia, Twenty has raised $138M from Accel, Caffeinated Capital, Friends & Family Capital, Point72 Ventures, General Catalyst, and In-Q-Tel.
  • You'll build the backend systems that power Twenty's cyber and electromagnetic capabilities-software that ingests real-time operational signals, models complex relationships, and serves high-throughput APIs at machine speed.
  • You'll design and ship reliable services in Go, working with known-hard problems like graph data modeling, event-driven architectures, and performance at scale.
  • You'll partner closely with product, frontend, and domain experts to turn operator needs into durable platform capabilities.
  • This role spans both cloud and on-premises environments supporting mission-critical U.S. national security outcomes.

Equal opportunity

  • equal opportunity employer.
  • If you need a reasonable accommodation during the hiring process, let us know and we will work with you.

Visa & Work Authorization

  • Government security clearance
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This listing is sourced directly from Twenty Twenty Therapeutics's careers page and normalized into a canonical job model.