Iambic Therapeutics

Sr Associate Scientist I or II, Medicinal Chemistry

San Diego HQ · Senior

Sponsorship not specifiedDetected 110 days ago

Machine LearningA/B TestingClinical TrialsResearchMass SpectrometryLeadership

About the role

We are seeking a highly skilled and motivated Senior Associate Scientist to join the Chemistry team at Iambic Therapeutics headquarters in San Diego.
This is a laboratory-based Associate Scientist position that requires strong technical expertise in organic synthesis, catalysis, and medicinal chemistry, as well as hands-on experience in the drug discovery process and a demonstrated "drug hunter" mindset.

Design, synthesize, purify, and characterize chemical compounds (10 mg-5 g scale) using modern analytical techniques such as LCMS, HPLC, and NMR, employing both individual and automated parallel synthesis approaches.
Identify and optimize reaction conditions using screening kits and other streamlined methodologies.
Collaborate with the high-throughput experimentation team to ensure the successful execution of parallel chemistry experiments.

BS in Chemistry with 5+ years experience (pharma/biotech) or MS in Chemistry with 3+ years experience (pharma/biotech).
Proven skills in multi-step organic synthesis, reaction optimization, SAR analysis, and scientific presentation.
Ability to thrive in a fast-paced, highly collaborative research environment.
Availability to work onsite in San Diego.

Prior exposure to high-throughput experimentation.
Familiarity with ADME-PK principles.
5+ years of experience contributing to drug discovery projects.
Experience with molecular modeling and structure-based drug design
The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action.
Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need.
Learn more about the Iambic team, platform, pipeline, and partnerships at iambic.ai http://iambic.ai.
The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences.

We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team.
Partner with computational chemists to leverage machine learning insights for efficient execution of the design-make-test cycle and platform development.

We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.

This listing is sourced directly from Iambic Therapeutics's careers page and normalized into a canonical job model.