Xaira Therapeutics
Software Engineer, X-Scientist
South San Francisco, California, United States · Mid
Stay score
odds of building a lasting career here
Sponsors, but it's cap-subject — you still face the weighted lottery (~61% per draw at Level IV). Good if you win; have a cap-exempt backup on your list.
Lottery odds assume a STEM candidate.
Personalize to your clock →H-1B wage level
the lottery is wage-weighted — each level is one more entry
$25,131 more — $165,131 — moves this role to Level II and 2 lottery entries. That figure is inside the range the employer already advertised.
Based on the DOL prevailing wage for this occupation and worksite, a base salary of $165,131 would place this position at wage Level II. That figure is within the posted range, and I'd like to target it. This role classifies under "Software Developers" for prevailing-wage purposes.
DOL prevailing wage, 2026-27 wage year · Software Developers (15-1252) · San Francisco-Oakland-Fremont, CA. Wage level is derived by USCIS from the offered wage, occupation and worksite; the occupation shown is inferred from the job title.
Employer immigration record
from this employer's Department of Labor filings
Files H-1B transfers
Sourced from Department of Labor LCA, PERM and prevailing-wage disclosure data. Employer matching is by name, so figures may be split across an employer's legal entities. Absence of a filing means none appears in our copy of the data, not that none exists.
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About the role
- On the X-Scientist team, you will work at the intersection of AI, software engineering, and therapeutic discovery.
- This role spans backend systems, APIs, tool-calling infrastructure, workflow orchestration, developer-facing SDKs and CLIs, and agentic interfaces that help scientists run analyses, inspect intermediate steps, and iterate on results.
Responsibilities
- Design reliable systems for long-running, multi-step workflows with strong testing, observability, logging, and maintainability.
- Collaborate with scientific and technical teams to turn complex research workflows into usable, extensible software.
- Experience building at least one of the following: a production library, CLI, API, SDK, backend service, workflow system, or developer platform.
- Xaira Therapeutics is an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.
- Our goal to build a diverse and inclusive team began on day one, and it will never end.
Requirements
- Familiarity with LLM application development, agent frameworks, tool calling, MCP-style interfaces, or orchestration systems.
- Comfort working with complex systems that combine multiple components, external calls, domain-specific logic, and evolving user needs.
- Strong communication skills and ability to work in a collaborative, multidisciplinary environment.
Nice to have
- Familiarity with biomedical databases or tools such as PubMed, UniProt, AlphaFold, PDB, DepMap, or related resources.
- Curiosity about biology and scientific research
- you do not need a biology background, but you should be excited to learn the domain and work closely with scientists and ML researchers.
- however, the base pay offered may vary depending on market, job-related knowledge, skills and capabilities, and experience.
- Xaira Therapeutics is an equal-opportunity employer.
- We believe that our strength is in our differences.
- TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes.
- Please do not forward resumes to our jobs alias or employees.
Skills
- About Xaira Therapeutics
- Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development.
- Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development.
- Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.
Compensation
- We offer a competitive compensation and benefits package, including base salary, bonus, and equity. The base pay range for this position is expected to be $140,000 - $215,000 annually
- however, the base pay offered may vary depending on market, job-related knowledge, skills and capabilities, and experience.
Company info
- We are building predictive and agentic AI systems across drug discovery, and the X-Scientist team accelerates this mission by making AI-assisted science reliable, usable, and scalable across drug discovery workflows.
- What We're Looking For
This listing is sourced directly from Xaira Therapeutics's careers page and normalized into a canonical job model.