Lycia Therapeutics

Lycia Therapeutics

Associate Director/Director, Clinical Science

South San Francisco · Director

Sponsorship not specified$190k-$280kDetected 175 days ago
GCPData AnalysisClinical TrialsClinical ResearchFDA RegulatoryResearchAnimal StudiesLeadershipCommunicationCollaborationMentoringBiostatisticsRegulatory Affairs

About the role

  • Lycia was established in 2019 in collaboration with academic founder and Nobel Laureate Carolyn Bertozzi, Ph.D., professor of chemistry and HHMI investigator at Stanford University.
  • In June, 2026, Lycia Therapeutics completed a $75 million Series D financing to advance its pipeline of LYTAC extracellular protein degraders into the clinic.
  • Lycia is headquartered in South San Francisco.

Responsibilities

  • Responsible for development of study protocols, case report forms (CRFs), consent forms, investigators brochure, development of charters (e.g., Independent Data Monitoring Committee, Safety Monitoring Committee) and other essential trial documents.
  • Collaborate with biostatisticians to interpret results and prepare clinical study reports for regulatory submissions.
  • Build relationships and engage with external stakeholders such as Key Opinion Leaders (KOLs), investigators, and regulatory authorities as needed to help advance the development of investigational products.
  • Support the preparation of regulatory documents (e.g., INDs, DSURs, NDAs) by providing clinical expertise.
  • These proteins drive a wide range of difficult-to-treat diseases, including autoimmune and inflammatory conditions.
  • Lycia Therapeutics is seeking a Director or Associate Director of Clinical Science who will play a critical role in the design, execution, and analysis of clinical trials of clinical stage assets.

Requirements

  • Director: MD/PhD or MD or equivalent advanced degree in life sciences or related field.

Nice to have

  • Minimum 5-8 years (Director) or 3-5 years (Associate Director) of experience in clinical research or drug development within biotech/pharma settings.
  • Expertise in allergy, immunology or autoimmune therapeutic areas is highly desirable.
  • Associate Director: Advanced degree (PhD, PharmD, RN, Master's) in life sciences
  • MD preferred but not required.

Skills

  • Strong understanding of drug development processes from preclinical to Phase 2 clinical development is desirable.
  • Proficiency in analyzing and interpreting complex clinical data.
  • Excellent communication skills for cross-functional collaboration and external stakeholder engagement.
  • Competencies and Capabilities
  • Location & Travel
  • San Francisco Bay Area preferred
  • Ability to work on-site (Lycia South San Francisco office) at least 2-3 full days per week
  • Business travel as needed (may vary with time, but is not expected to exceed 15%)
  • San Francisco Bay Area preferred; Ability to work on-site (Lycia South San Francisco office) at least 2-3 full days per week

Compensation

  • $190k-$280k

Benefits

  • Act as a medical monitor or scientific liaison during studies, depending on qualifications, to partner with investigators, study site staff, and CRO partners,
  • Participates in and leads safety and data cleaning activities (medical listing review, periodic safety review, preparation for IDMC review).

Company info

  • Lycia Therapeutics is a biotechnology company using its proprietary lysosomal targeting chimera (LYTAC) platform to discover and develop best-in-class therapeutics that degrade extracellular and membrane-bound proteins.

This listing is sourced directly from Lycia Therapeutics's careers page and normalized into a canonical job model.