Arc Institute

Arc Institute

Postdoctoral Researcher, Horns Lab

Palo Alto, CA

Sponsorship not specifiedDetected 40 days ago
PythonFull-Stack DevelopmentComputer VisionElectrical EngineeringBioinformaticsMolecular BiologyScientific WritingResearchAnimal StudiesAnimal ModelsCommunication

About the role

  • About Arc Institute Arc Institute is an independent nonprofit research organization at the interface of artificial intelligence and biology, working to accelerate scientific progress and understand the root causes of complex diseases.
  • Arc's Technology Centers and Core Investigator labs work side by side, integrating experimental and computational biology under one roof to tackle problems neither could solve alone.
  • More than 300 Arconauts work together at our Palo Alto headquarters, backed by substantial long-term philanthropic funding.

Responsibilities

  • Design, execute, and analyze experiments; take end-to-end ownership of a research project within the lab's scientific focus, with guidance from the PI and increasing independence as you develop expertise.
  • Publish first-author papers in high-impact journals, present at national and international conferences, and build a network of collaborators across Arc, Stanford, and beyond.\
  • Mentor and train research associates, technicians, and students; engage in Arc-wide activities (seminars, symposia); contribute to a collaborative research environment; maintain rigorous experimental records and documentation; and contribute to lab operations including protocol development and maintaining shared infrastructure.
  • Mapping the genes, pathways, and environmental factors behind Alzheimer's disease to develop drug candidates that address root causes.
  • We build new tools and use them to discover mechanisms in complex, dynamic systems, including the immune system, the brain, and other tissues.
  • Postdocs in the lab are encouraged to lead ambitious, independent projects, resulting in high-impact publications, and to prepare for long-term careers in academia or industry.

Requirements

  • Excellent written and verbal communication skills, including a track record of scientific writing (manuscripts, preprints, or equivalent).
  • Demonstrated ability to work in a fast-paced environment and be both an independent thinker and a highly collaborative team player.
  • You are extremely curious and self-motivated.
  • You are intellectually independent and enjoy proposing and driving new research directions (with input from your PI).
  • You are eager to learn and adopt new techniques.
  • You are excited to solve puzzles that have translational impact and/or enable new discovery and therapeutic approaches.
  • You have a strong foundation in synthetic biology or genomics technology development, and/or in immunology or neuroscience.

Nice to have

  • Our research group thrives on bringing together people with diverse expertise.
  • The best fit is typically someone strong in at least one area and excited to learn the others.
  • Experience in one or more of the following is a plus:
  • Single-cell sequencing and analysis (scRNA-seq, scATAC-seq, CITE-seq)
  • Spatial transcriptomics and multi-omics
  • Pooled perturbation screens (CRISPRi/a/KO, Perturb-seq)
  • Immune cell biology or engineering
  • Immune receptor biology and profiling

Skills

  • Mammalian synthetic biology
  • Single-cell and spatial multi-omics
  • Engineering and mechanistic study of EVs, VLPs, and other delivery systems
  • Immune cell engineering and functional assays
  • Sequencing-based measurement technologies
  • Computational analysis and modeling of high-dimensional datasets

Compensation

  • Brief cover letter describing your research interests, what kinds of projects you're excited to lead, and why the Horns Lab is a fit. Please be sure to include contact information for 3+ references.

Benefits

  • Our lab develops and applies technologies that bridge synthetic biology and genomics to answer fundamental and translational questions in human health, with a particular emphasis on immunology and neuroscience.

Company info

  • About Arc Institute
  • Arc Institute is an independent nonprofit research organization at the interface of artificial intelligence and biology, working to accelerate scientific progress and understand the root causes of complex diseases.
  • Founded in 2021 and based in Palo Alto, Arc partners with Stanford University, UC Berkeley, and UC San Francisco.
  • Unlike academia, our scientists have long-term funding and industry-like resources.
  • Unlike industry, they're free to pursue high-risk, long-term research without commercial pressures.
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This listing is sourced directly from Arc Institute's careers page and normalized into a canonical job model.