Xaira Therapeutics

Xaira Therapeutics

BioMedical AI Research Engineer

South San Francisco, California, United States

Sponsorship not specified$190k-$280kDetected 76 days ago
PythonMachine LearningTensorFlowPyTorchLLMsRAGAgentic AIAI OrchestrationBioinformaticsResearch

About the role

  • This role goes beyond traditional LLM + RAG pipelines.
  • Architect scalable systems that combine structured and unstructured biomedical data within production-grade AI environments.

Responsibilities

  • Design and implement agentic AI architectures capable of multi-step reasoning, planning, and tool use in biomedical contexts.
  • Develop LLM-based agents that dynamically retrieve, rank, and synthesize knowledge from scientific literature, knowledge graphs, omics datasets, and clinical data.
  • Build memory and feedback mechanisms that allow agents to refine hypotheses, update context, and adapt to evolving data.
  • Collaborate closely with computational biologists, translational scientists, and software engineers to embed agentic systems into real-world discovery pipelines.
  • You will build AI agents that can retrieve, synthesize, evaluate, and act on biomedical information across literature, omics datasets, and clinical records operating as intelligent systems embedded within discovery workflows.
  • Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.
  • Our goal to build a diverse and inclusive team began on day one, and it will never end.

Requirements

  • Strong hands-on experience with large language models, including fine-tuning, alignment, and structured prompting.
  • Proficiency in Python and modern ML frameworks (PyTorch, JAX, TensorFlow).
  • Experience working with large-scale biomedical datasets (genomics, transcriptomics, clinical records, or scientific corpora).
  • Degree in Computer Science, Machine Learning, Computational Biology, Biomedical Informatics, or related field.
  • Experience building agent-based systems or complex LLM orchestration frameworks (e.g., multi-agent systems, tool-using LLMs, planning modules).
  • Preferred
  • Experience designing autonomous research assistants or AI systems that perform multi-step scientific reasoning.
  • Familiarity with knowledge graphs, hybrid symbolic-neural systems, or multimodal foundation models.
  • Understanding of privacy, security, and regulatory considerations in healthcare AI.

Skills

  • About Xaira Therapeutics
  • Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development.
  • Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development.
  • Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.
  • Integrate external tools (analysis pipelines, simulation engines, statistical models, databases) into autonomous agent workflows.

Compensation

  • We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers.
  • We offer a competitive package that includes base salary, bonus, and equity.
  • The base pay range for this position is expected to be $190,000 - $280,000 annually
  • however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.

Benefits

  • A Summary of Benefits is available for all applicants.

This listing is sourced directly from Xaira Therapeutics's careers page and normalized into a canonical job model.