Roche
Scientist 2, Biochemical and Cellular Pharmacology
South San Francisco
Sponsorship not specified$86k-$159kDetected 1 day ago
PythonData AnalysisExcelRoboticsPharmacologyFlow CytometryResearchProtein AnalysisProblem SolvingTime ManagementPublic Speaking
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33Unrated
Cap-exempt (no lottery)0
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Entry-level history0
PERM / green-card track0
Lottery odds (Level III)83
Fits your clock70
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About the role
- Join Genentech's Biochemical and Cellular Pharmacology Department and help shape the future of cardio-metabolic therapeutics.
Responsibilities
- Operating at the intersection of cutting-edge science and drug development, you will support the selection and characterization of therapeutic candidates across our pipeline.
- In this role, you will develop, validate, and execute sophisticated biochemical and cell-based assays in heterologous and physiologically relevant systems to evaluate drugs in cardiovascular, renal and metabolic areas.
- You will support projects from initial lead finding through optimization, conducting detailed mechanistic studies on complex receptor signaling pathways and protein interactions.
- Ultimately, your scientific insights will help define target candidate profiles and shape the screening cascades that deliver our next-generation therapeutics.
- Pioneer novel assay platforms that interrogate complex receptor pharmacology and mechanism of action, showing scientific curiosity and reviewing literature to drive your initiatives
- Drive automation and efficiency using laboratory robotics (Bravo, Tecan, Echo…) to streamline workflows and accelerate timelines
- Collaborate across multidisciplinary teams in a fast-paced environment, generate high-quality presentations, and communicate findings to stakeholders
Requirements
- Bachelor's degree and/or Master's degree in Cell Biology, Pharmacology, Biochemistry, or related field
- 5+ years of hands-on research experience in fast-paced pharma or biotech environments
- Expert-level proficiency with culture of mammalian cells, primary cells, and stable cell line generation
- Hands-on experience with a variety of microplate-format biochemical and cellular assays (e.g., HTRF, AlphaScreen, or luminescence-based readouts)
Nice to have
- Expertise in the cardiovascular, renal, or metabolic disease field
- Experience with flow cytometry, ELISA assays, or high-content image analysis
- Experience with lab automation and high-throughput screening
- Proficiency with data analysis software and visualization tools (GraphPad Prism, Genedata, Excel, Python, R)
Compensation
- The expected salary range for this position based on the primary location of South San Francisco, CA is $85,500 to $158,700.
Company info
- We are seeking a creative, motivated scientist to drive the discovery and characterization of innovative drug candidates that could transform patient outcomes.
Equal opportunity
- equal opportunity employer.
- If you have a disability and need an accommodation in relation to the online
This listing is sourced directly from Roche's careers page and normalized into a canonical job model.