Spyre Therapeutics

Spyre Therapeutics

Senior Medical Director, Clinical Development

US- Remote · Director

Sponsorship not specified$343k-$365kDetected 7 days ago
GCPStatisticsClinical TrialsFDA RegulatoryResearchExperimental DesignLeadershipCommunicationCollaborationBiostatisticsRegulatory Affairs

About the role

  • Spyre's pipeline includes investigational extended half-life antibodies targeting α4β7, TL1A, and IL-23.
  • Role Summary: The Senior Director of Clinical Development for Rheumatology will contribute to the clinical development strategy and execution for innovative therapies targeting rheumatic indications.
  • The expected salary range offer for this role is $343,000 to $365,000.

Responsibilities

  • Trial Management: Contribute to the study design, execution and interpretation of results, with a focus on proof-of-concept and later phases of development.
  • Cross-functional Collaboration: Work closely with cross-functional teams including Biostatistics, Regulatory Affairs, and Clinical Operations to support integrated and strategic trial execution.
  • Excellent communication and interpersonal skills, with the ability to motivate teams and collaborate effectively across functions.
  • Ability to manage complex projects in a fast-paced environment.
  • We also embrace differences in experience and background, and welcome diversity of opinions and thought with active recruitment designed to create a stronger and better Spyre that is focused on developing life-changing products for patients.

Requirements

  • Other activities as required.
  • Ideal Candidate:

Nice to have

  • Minimum of 4+ years clinical development experience within the pharmaceutical or biotech industry within I&I indications, rheumatology strongly preferred.
  • Experience with antibody therapeutics preferred.
  • Proven track record in designing and executing clinical trials in immunology or inflammation.
  • Strong understanding of GCP, clinical trial design, statistics, and global regulatory processes.

Compensation

  • Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits.
  • The expected salary range offer for this role is $343,000 to $365,000.

Benefits

  • Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits.
  • Provide scientific/medical content and other input as appropriate for INDs, Investigator Brochures, Clinical Study reports, regulatory submissions and responses, and other program documents.
  • Ensure compliance with regulatory standards and guidelines, including health authority requirements for MD sign-off on patient-related matters.
  • Clinical Leadership: Contribute strategic leadership and medical expertise to the clinical development of our cutting-edge antibody portfolio in rheumatic indications.
  • Actual pay offered may vary depending on job related knowledge, experience, education, and geographic location.

Company info

  • Spyre Therapeutics is a clinical-stage biotechnology company committed to developing next-generation therapies that elevate the standard in immunology by delivering more complete disease control, greater durability, and a simpler treatment experience for patients.

Equal opportunity

  • As an equal opportunity employer, Spyre is committed to a diverse workforce.

This listing is sourced directly from Spyre Therapeutics's careers page and normalized into a canonical job model.