Iambic Therapeutics

Machine Learning Scientist – Clinical Prediction

Boston Office

Sponsorship not specifiedDetected 33 days ago

PythonDockerKubernetesMachine LearningDeep LearningData ScienceNLPA/B TestingClinical TrialsPharmacovigilanceResearch

About the role

We are seeking a Machine Learning Scientist to join the Enchant team at Iambic Therapeutics.
This role spans data sourcing through to production deployment.

Identify, characterize, and utilize datasets that can deliver insights into pharmacokinetics (PK), pharmacodynamics (PD), toxicity, clinical adverse events, and clinical trial outcomes
Develop and apply rigorous experimental approaches that account for multiple sources of potential leakage (split, metadata, trial-family, temporal, ontological, arm-comparator, etc.)
Design and maintain benchmarking and evaluation frameworks that track model quality across models and tasks
Build models with appropriate calibration, uncertainty quantification, and clinically meaningful evaluation metrics.
Collaborate with ML and software engineering colleagues to deploy and operationalize models
Partner with clinical scientists and pharmacologists to ensure model development is grounded in drug discovery and development needs
Communicate results to internal teams, external partners, and at conferences
Generate high-quality research and engineering code: refactor, test, document, and package ML components to support team velocity
refactor, test, document, and package ML components to support team velocity

MS in chemistry, bio/chemical engineering, or a computational STEM field with 3+ years of relevant industry or research experience, or PhD or equivalent industry experience demonstrating comparable depth
Demonstrated experience in clinical science or working with clinical datasets
Comfort working with modern ML infrastructure (e.g., Docker, CUDA, Kubernetes, experiment tracking such as Weights & Biases)

Familiarity with ClinicalTrials.gov/AACT http://ClinicalTrials.gov/AACT data
Experience with MedDRA, pharmacovigilance, or adverse event data
Hands-on experience with agentic data extraction
HPC or large-scale computing experience
The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action.
Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need.
Learn more about the Iambic team, platform, pipeline, and partnerships at iambic.ai http://iambic.ai.
The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences.

We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team.
Strong Python experience, including implementing and fine-tuning deep learning models

We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.

This listing is sourced directly from Iambic Therapeutics's careers page and normalized into a canonical job model.