Pathos AI
Director, Clinical Science
New York City, NY · Director
Sponsorship not specifiedDetected 27 days ago
GCPAgentic AIFDA RegulatoryExperimental DesignLeadership
About the role
- The Director, Clinical Science is a hands-on member of the Clinical Development team, responsible for the day-to-day scientific execution of Pathos oncology programs across active Phase 1 and Phase 2 trials.
- You will work closely with Clinical Operations, Translational Medicine and Biomarker Science to keep studies running with scientific rigor at every step.
- That means you spend your time on the science reviewing data, resolving eligibility questions, sharpening protocols, and making the calls that move programs forward, not on administrative overhead.
Responsibilities
- Own protocol development and clinical documents Author and own study protocols from first draft through amendments, including study design, eligibility criteria, endpoint selection, and safety monitoring plans.
- Direct AI agents to compile source data, structure document drafts, and run quality checks, then apply your scientific judgment to finalize each deliverable.
- Lead data review and monitoring Conduct ongoing review of safety and efficacy data across active studies, including eligibility confirmation, protocol deviation assessment, and adverse event review.
- Prepare materials and lead deliverables for data monitoring committees and other clinical review bodies.
- Collaborate with data management on eCRF development, edit check design, and database lock activities.
- Support trial execution and site interactions Serve as the scientific point of contact for clinical investigators during study startup, conduct, and closeout.
- Maintain GCP compliance and audit-ready trial conduct across all assigned programs.
- Pathos is building a next-generation biotech with AI at the core.
- If you have spent your career building and shipping AI systems at scale, this is the environment where that experience becomes a superpower.
- You own protocol development, data review, clinical document authorship, and site-level scientific support from study startup through closeout.
Requirements
- MD, PhD or PharmD in a relevant life science discipline required.
- Experience in solid tumor oncology
- Comfort working with AI generated analyses, real world evidence, and computational predictions as inputs to scientific and clinical decisions.
- Experience contributing to clinical development plans for multiple concurrent programs in a fast moving organization.
Benefits
- Write and maintain Investigator Brochures, informed consent forms, Clinical Study Reports, and briefing documents in partnership with Clinical Operations and Medical Writing.
- Support responses to Health Authority questions with accurate, well-reasoned clinical and scientific rationale.
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This listing is sourced directly from Pathos AI's careers page and normalized into a canonical job model.