miraibio

Associate Scientist/Scientist I, LNP Formulations

Cambridge, MA

Sponsorship not specified$96k-$127kDetected 6 days ago

Machine LearningData AnalysisComplianceRecruitingResearchAnimal StudiesCommunicationProblem Solving

About the role

Mirai Bio is seeking a scientist to advance our lipid nanoparticle (LNP) delivery platform for nucleic acid therapeutics.
The successful candidate will contribute to both platform innovation and preclinical pipeline programs, working at the interface of formulation science, Chemistry, analytical characterization, and process development.

Design, formulate, and characterize lipid nanoparticle (LNP) systems for nucleic acid delivery across early research and preclinical development stages
Develop and optimize formulation processes, including microfluidic mixing and scale-up approaches (e.g., TFF, ultrafiltration)
Generate high-quality, reproducible data and maintain thorough documentation in electronic lab notebooks
Prepare LNP formulations to support internal research and partner programs
Collaborate cross-functionally with analytical, translational, and Tech development teams to advance platform goals

Level (Associate Scientist or Scientist I) will be determined based on experience, technical expertise, and demonstrated impact.
Hands-on experience in nanoparticle or LNP formulation and characterization
Strong understanding of drug delivery systems, particularly for nucleic acid therapeutics
Experience with nanoparticle characterization techniques (e.g., DLS, zeta potential, fluorescence-based assays such as Ribogreen, chromatography)
Ph.D. and 0-1 years or 4+ years (M.Sc.) or 6+ years (B.Sc.) of relevant industry experience in LNP formulation optimizations and drug delivery with strong background in nucleic acid therapeutics and education in life sciences or engineering (Pharmaceutical Sciences, Biomedical Engineering, Biochemistry, etc)
Demonstrated ability to design, execute, and troubleshoot experiments independently
Strong data analysis, documentation, and communication skills

Familiarity with formulation process technologies (e.g., microfluidic mixers, pumping systems, TFF)
Experience with high-throughput formulation screening approaches
Experience supporting in vivo studies or translating formulations from research to preclinical scale
Scientific rigor and attention to data quality and reproducibility
Curiosity and a problem-solving mindset
Ability to work both independently and collaboratively in a fast-paced environment
Clear and concise communication across disciplines
Ownership and accountability in driving projects forward

Mirai Bio currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits.

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond.
vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.

Mirai Bio is a privately-held, Flagship-founded biotechnology company that is delivering genetic medicines from promise to performance.
At Flagship, we accept impossible missions to enable bigger leaps.

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This listing is sourced directly from miraibio's careers page and normalized into a canonical job model.