Generate Biomedicines

Scientist I / Scientist II, Computational Protein Design

Somerville, MA · Mid

Sponsorship not specifiedDetected 7 days ago

Machine LearningAgentic AIBioinformaticsResearch

About the role

You will join a talented and collaborative group of ML scientists, engineers, and wet-lab scientists dedicated to redefining how medicines are made.
You don't just run existing tools; you understand what's missing from current approaches and are driven to fill those gaps.
This role is based in our Somerville, MA office with flexibility for hybrid work.

develop, validate, and productionize de novo protein generation protocols and optimization techniques on our experimental platform, using measured data in-the-loop to iteratively refine models across modalities and therapeutic applications.
design, interpret, and implement biophysical and functional metrics for evaluating generated designs, leveraging existing literature, adapting known metrics to new contexts, and performing original research to benchmark and deploy new scoring approaches.
work closely with experimental colleagues, biologists, and clinical scientists to define design objectives, interpret experimental readouts, and guide iterative design-build-test-learn cycles that advance programs.
PhD in Computational Biology, Biophysics, Computer Science, or a related field, with demonstrated experience in protein design applications.

0-2 years of experience applying computational and/or ML methods to protein design, modeling, or prediction.

We are seeking a creative, motivated Computational Protein Design Scientist to join our Model-Driven Design team at Generate:Biomedicines.

This listing is sourced directly from Generate Biomedicines's careers page and normalized into a canonical job model.