Vor Bio

Vor Bio

Senior Director Health Economics and Outcomes Research (HEOR)

Boston, MA · Director

Sponsorship not specifiedDetected 51 days ago
Vendor ManagementPublic HealthFDA RegulatoryScientific WritingResearchLeadershipCommunicationCollaborationEpidemiologyRegulatory Affairs

About the role

  • When you join Vor, you're not just working on a medicine.
  • Impact: Contribute directly to a medicine with best-in-disease Phase 3 results in myasthenia gravis and expansion into multiple autoimmune diseases.
  • In this role you will need to anticipate payer needs and shape development accordingly.

Responsibilities

  • Build a fit‑for‑purpose HEOR roadmap including burden of illness, cost‑of‑illness, treatment patterns, PRO strategy, economic models, and RWE plans.
  • Design and oversee RWE studies, including natural history studies, chart reviews, registries, and external data collaborations.
  • Lead development and validation of patient‑reported outcomes (PROs) and other clinical outcome assessments (COAs) for regulatory and payer use.
  • Partner with Clinical Development to ensure trial designs incorporate endpoints relevant to payers, HTA bodies, and patient communities.
  • Manage vendors conducting HEOR and RWE studies
  • Value Demonstration & Market Access Support
  • Lead development of global value dossiers (GVDs), AMCP dossiers, payer evidence decks, and HTA submissions.
  • Manage vendors conducting HEOR and RWE studies; ensure scientific rigor, compliance, and timely delivery.
  • Support payer and HTA engagements with evidence, models, and scientific responses.
  • Collaborate with Market Access on payer strategy, pull‑through materials, and field training.

Requirements

  • 10+ years of HEOR/RWE experience in biotech/pharma, with at least 5 years in a leadership or strategic role.
  • Deep expertise in economic modeling, RWE methodologies, PRO/COA development, and payer/HTA evidence requirements.
  • Proven ability to operate in lean, ambiguous, high‑growth environments.
  • Experience in rare disease, autoimmune diseases or high‑cost specialty products.
  • We invite you to come as you are.
  • Advanced degree (PhD, PharmD, MD, MPH, MS) in health economics, epidemiology, outcomes research, public health, or related field.
  • Demonstrated success supporting pre‑launch and launch activities, ideally in rare disease or specialty therapeutics.
  • Strong vendor management, scientific writing, and communication skills.
  • Familiarity with US and ex‑US pricing and reimbursement landscapes.
  • The salary range for the Senior Director, Health Economics and Outcomes Research is expected to be between $280,000 and $310,000 per year. Individual pay may vary based on multiple factors including but not limited to relevant job-related skills, experience, education or training, market factors, and work location.
  • At Vor, we support our team with robust benefits, including comprehensive health coverage, flexible paid time off, generous parental leave, and a competitive 401(k). From education assistance to wellness resources and financial security, we invest in your well-being so you can thrive at work and beyond.
  • As an equal opportunity employer, we at Vor Bio know that diversity inspires innovation, inclusiveness, and creativity. We invite you to come as you are. All applicants will be considered for employment agnostic to race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
  • Please visit our website at https://www.vorbio.com/ for more information.

Compensation

  • The salary range for the Senior Director, Health Economics and Outcomes Research is expected to be between $280,000 and $310,000 per year.

Benefits

  • Develop and own the global and US HEOR strategy, aligned with clinical development, Medical Affairs, and Market Access priorities.
  • Build and maintain cost‑effectiveness models, budget impact models, and scenario analyses to support pricing and reimbursement.
  • Partner closely with Medical Affairs on evidence generation, publications, and scientific exchange.

Company info

  • Be part of a rapidly scaling company with opportunities to grow your career in science, clinical development, commercial strategy, and beyond.
  • At Vor, we believe science can do more than manage symptoms.
  • By advancing telitacicept, a first- and potentially best-in-class dual BAFF/APRIL inhibitor, we are silencing upstream survival signals and stopping downstream autoimmune cascades.
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