Vaxcyte
Associate Scientist II (Contract), Research
San Carlos, California, United States · Mid
Sponsorship not specifiedDetected 29 days ago
Molecular BiologyResearchCommunicationCollaboration
About the role
- Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked.
- Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning.
- Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.
Requirements
- BS in Biochemistry, Molecular Biology or a relevant science considered, with minimum of 2 years of relevant industry experience or MS with minimum of 1 year of relevant industry experience.
- Experience with diverse protein targets, bacterial and eukaryotic recombinant proteins, small/large subunit vaccine antigens, fusion proteins, multimeric complexes, glycoproteins, and VLPs.
- Familiarity with automation or high throughput workflows such as (96-well plates) and UNICORN/AKTA software DoE integrations.
- Experience in process development.
- Applicants must have practical, hands-on experience with multiple chromatographic modalities (not limited to monoclonal antibody/Protein A workflows).
- Experience should include selection, screening, development, scale-up and characterization of various chromatography techniques.
Nice to have
- Immobilized metal affinity chromatography (IMAC)
- Ion-exchange chromatography (IEX)
- Hydrophobic interaction chromatography (HIC)
- Size-exclusion chromatography (SEC)
- Hydroxyapatite (CHT / HA)
- Designing chromatography trains to reduce host cell protein, endotoxin and aggregates using complementary modalities.
- Demonstrated DoE experience for multimodal optimization is a plus.
- Membrane chromatography for high-throughput contaminant removal or virus/VLP processing and as a scale-friendly polishing/scavenging step.
Company info
- $51/hr. - $56/hr.
- We are an equal opportunity employer.
- All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.
- Join our Mission to Protect Humankind!
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This listing is sourced directly from Vaxcyte's careers page and normalized into a canonical job model.