Alta Resource Technologies, Inc.
Principal Scientist, Protein Engineering
Boulder, CO · Principal
No sponsorship$130k-$170kDetected 7 days ago
Data AnalysisData ScienceSupply ChainMolecular BiologyExperimental DesignLeadershipCommunicationCritical ThinkingFermentation
About the role
- About Alta Alta Resource Technologies (Alta) is a next generation mining company that uses synthetic biology to separate critical minerals from conventional and unconventional resources, including e-waste.
- The exponential growth of new tech industries, as well as the information technology sector, are driving historic growth in mineral demand and stressing existing supply streams.
- Meeting new demand, diversifying the supply chain, and producing minerals in a more sustainable manner requires the rapid development, deployment and scaling of new technologies.
Responsibilities
- Develop and optimize high throughput protein engineering workflows
- Establish construct design and cloning workflows that enable high-throughput and multiplexed approaches for protein variant testing and selections.
- Develop high-throughput variant libraries for improving strain and protein performance including optimizing for protein production, affinity, specificity, and stability.
- Develop and implement automation and experimental strategies to support high-throughput and library-scale directed evolution campaigns.
- Collaborate with the team to develop end-to-end processes designed for workflow efficiency.
- Develop and implement scale-up protein production workflows
- Apply data analysis from directed evolution campaigns to inform scale-up production of lead protein candidates.
- Design and implement protein production improvements to achieve round-over-round improvement.
- Develop talent through team building and project execution.
- We believe that varied perspectives, experiences, and backgrounds strengthen our team and drive better outcomes for our clients and partners.
Requirements
- Ph.D. in biochemistry, molecular biology, or related field with 10+ years of industry experience.
- Expertise in high-throughput molecular biology approaches and library-scale workflows.
- Experience in microbial bioproduction.
- Deep knowledge of classic and state-of-the-art molecular biology and multiplex library-scale approaches to directed evolution campaigns.
- Strong written and verbal communication skills and ability to work within different teams.
- Please note: Applicants must be authorized to work for ANY employer in the U.S.
- Applicants must be authorized to work for ANY employer in the U.S.
Nice to have
- Experience with metalloprotein biochemistry.
- Experience with bioconjugate chemistry.
- Experience with fermentation and down-stream processing.
- Proficiency in working with data science teams for scripting pipelines and bioinformatics.
- A mission-driven, high-trust team operating at the intersection of innovation, national security, and sustainability.
Compensation
- The starting pay range for this position is $130,000 - $170,000 and is commensurate with educational background and work experience.
Benefits
- Compensation & Benefits
- The starting pay range for this position is $130,000 - $170,000 and is commensurate with educational background and work experience.
- Benefits include:
- Medical, Dental, Vision plans (or equivalent)
- Flexible Time Off
- Paid Parental Leave
- Paid Sick Leave
Equal opportunity
- Alta Resource Technologies is an equal opportunity employer committed to building a workforce that reflects the diversity of the communities we serve.
- equal opportunity employer committed to building a workforce that reflects the diversity of the communities we serve.
Visa & Work Authorization
- Please note: Applicants must be authorized to work for ANY employer in the U.S.
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