Dyne Therapeutics

Senior Director, Portfolio Reporting & Analytics

Waltham, MA · Director

Sponsorship not specified$233k-$285kDetected 21 days ago

AlgorithmsGCPMachine LearningData ScienceStatisticsForecastingResearchAnimal StudiesCommunicationGxPBiostatisticsEpidemiology

About the role

Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases.
The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease.
Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.

Implement scalable operational data governance (metadata, master data, standards) aligned with R&D operating models and GxP expectations
Develop streamlined, standard analytical frameworks and methodologies (definitions, metric specifications, visualization standards) to drive consistency and comparability across the organization
Develop predictive country and site selection analytics to optimize trial delivery (start-up speed, enrollment yield, data quality, cost) and inform feasibility and country footprint decisions

Bachelor's degree in quantitative or life sciences field (e.g., Statistics, Data Science, Engineering, Operations Research, Epidemiology, Pharmacy, Biology).
Demonstrated expertise with portfolio, program, and study KPIs, operational planning and plan vs. actual analysis, and scenario modeling for timelines, costs, risks, and resources
Hands-on experience with advanced analytics/ML (forecasting, simulation, optimization) and turning algorithms into operational tools that drive business decisions
Strong understanding of the clinical development lifecycle, including feasibility, site activation, enrollment, data management, monitoring, and close-out
Exceptional ability to influence without direct authority across all organizational levels, including senior functional leaders
Exceptional verbal and written communication skills, with the ability to convey complex information clearly to diverse audiences (written, verbal and presentation)
Ability to interpret and communicate complex data to diverse audiences

experience with site/country selection analytics, enrollment prediction, and vendor performance analytics
Familiarity with R&D systems (e.g., CTMS, EDC, eTMF, RTSM, safety, eCOA), portfolio/financial planning (e.g., enterprise planning tools), and HR capacity planning
Background in data governance (metadata, MDM), data product management, and adoption at scale
Excellent team player
Strong decision maker
Ability to work in a matrix environment
Ability to work independently as a hands-on manager, proactively contribute as a resource when necessary
High level of integrity, compliance, ethics, and transparency

Establish a study-level insights platform that leverages structured operational data to provide site- and PI-level insights (enrollment health, quality, cost, competitive trial density) to study teams and vendor partners
Drive change management and adoption of new analytics capabilities, ensuring insights are embedded in business rhythms (governance reviews, QBRs, portfolio prioritization, study health checks)
Excitement about Dyne's vision and mission

We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease.
At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities.
Flexibility to adapt and meet the changing/growing needs of our customers

This listing is sourced directly from Dyne Therapeutics's careers page and normalized into a canonical job model.