Gsk

Gsk

Oligo Discovery Chemistry Principal Scientist

USA - Massachusetts - Cambridge · Principal · Full-time

Sponsorship not specified$121k-$202kDetected 6 days ago
Data AnalysisComputer VisionProcurementHRMass SpectrometryCommunicationMentoringOrganizational Skills

About the role

  • Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives.
  • We're uniting science, technology, and talent to get ahead of disease together.
  • Job Description The successful candidate will help to establish pre-clinical capabilities within GSK's new oligo synthesis lab.

Responsibilities

  • Perform hands-on work, establish small molecule, lipid, linker, and other synthetic workflows including designing structure activity relationship studies, implementing synthetic routes, and drafting SOPs in support of next generation chemistry and method development.
  • Develop and maintain SOPs for synthesis, processing, and purification to ensure high-quality, reproducible results.
  • Collaborate and communicate across various teams to build robust study designs and workflows, or leverage internal resources to deliver on portfolio endpoints.
  • This role will provide YOU the opportunity to lead key activities to progress YOUR career.
  • Team-focused with strong initiative and ability to troubleshoot challenges and implement novel solutions.
  • Demonstrated ability to maintain a high level of integrity while balancing multiple priorities and responsibilities.
  • Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Requirements

  • Experience with HPLC purification techniques such as reverse phase, size exclusion, ionic chromatography potentially using Agilent, Waters, or Cytiva ÄKTA Avant and Pure purification systems, and LC/MS analytics.
  • Prior experience with scientific and professional mentorship and project leadership.
  • All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK.

Nice to have

  • Excellent written and verbal communication skills, attention to detail, organizational skills, and the ability to collaborate effectively with a team are required.
  • Prior experience with oligonucleotide synthesis and nucleoside chemistry is desirable but not required.
  • Demonstrable sense of urgency, flexibility, independence and accountability.
  • Must be a committed team player prepared to work in and embrace a team-based culture.
  • If you have the following characteristics, it would be a plus:

Skills

  • Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
  • Uniting science, technology and talent to get ahead of disease together.
  • GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together.
  • GSK is an Equal Opportunity Employer.
  • Important notice to Employment businesses/ Agencies
  • GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site.
  • This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements.
  • For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Compensation

  • If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $121,275 to $202,125.

Benefits

  • At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade.
  • respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.
  • We look forward to learning how your skills and experience can help us get ahead of disease together.
  • The US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role.
  • In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role.
  • Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.
  • We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive.
  • and infectious diseases - to impact health at scale.

Equal opportunity

  • If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments@gsk.com
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