Zealandpharma

Global Head of Drug Substance

Cambridge, MA, US

Sponsorship not specifiedDetected 1 day ago

Machine LearningComputer VisionProcess ImprovementClinical TrialsGMPResearchLab ResearchLeadershipCollaboration

About the role

Your new position Zealand Pharma is looking for a Global Head of Drug Substance - Senior Director, based in Boston.
In Boston, the role will establish a process wet lab staffed with process scientists focused on hands-on peptide process development and optimization.

Establish and lead the Peptide Process Development lab in Boston, including hiring and developing a high-performing local team
Lead synthetic route scouting and salt selection, evaluating alternative processes with yield, COGS, manufacturability, and scalability as key decision criteria
Develop and optimize upstream and downstream process design to establish scalable, cost-effective synthetic routes fit for initial clinical trials and as the foundation for Phase 3
Partner closely with Analytical Development and Manufacturing to ensure processes are scalable, robust, and sustainable
Drive technology transfer in collab with DK drug substance team to external CMOs, ensuring seamless transition from development to production
Demonstrated leadership experience managing and developing cross-functional or global technical teams
Experience defining manufacturing strategies from early discovery to Phase 2, with an eye toward building a robust foundation for Phase 3 and commercial
A pragmatic problem-solver and strategic thinker, this person thrives in a dynamic, build-phase environment and can balance hands-on technical depth with cross-functional influence.
Your new team This role leads a globally distributed Drug Substance organization spanning two sites.
From discovering and developing the best new peptide drugs for patients, to engaging with our partners or connecting with each other.

If this sounds like you, and you are ready to shape the future of peptide drug substance development at a fast-growing biotech, then you could be our new colleague.
Your profile The ideal candidate brings a track record of scientific excellence in peptide process chemistry combined with the leadership presence to inspire and grow a team.
While a cover letter is not required, please include a few sentences in your CV explaining your motivation for applying.

Advanced degree (PhD preferred) in Chemistry, Chemical Engineering, or a related field, with extensive experience in peptide process development

ZEAL) is a biotechnology company focused on advancing medicines for obesity and metabolic health.
Combining more than 25 years of peptide R&D expertise with a proprietary data platform that leverages advanced data-driven and AI/ML approaches, Zealand Pharma aims to lead a new era in obesity and metabolic health.

Making bonds is at the core of everything we do.
Founded in 1998, Zealand Pharma is headquartered in Copenhagen, Denmark, with a U.S. presence in Boston, Massachusetts.

This listing is sourced directly from Zealandpharma's careers page and normalized into a canonical job model.