Legend Biotech
Senior Scientist/Principle Scientist– Cell Biology and Immunology
Piscataway, NJ, United States · Senior
Sponsorship not specifiedDetected 2550 days ago
SparkCRISPRFlow CytometryCell CultureResearchProtein AnalysisCommunicationPublic Speaking
About the role
- Legend Biotech is a clinical stage biopharmaceutical company focused on the discovery and development of novel cell therapies for oncology, immunology and infectious disease indications.
- We are currently seeking talented and motivated individuals to join the group of Cell Biology and Immunology in the R&D Department located at Piscataway of New Jersey.
- The successful candidate should possess extensive knowledge and hands-on experience in oncology, cell biology and immunology, in particular TCR-T/CAR-T cell biology.
Responsibilities
- Independently plan, design, execute experiments to assess the in-vitro functions of TCR-T/CAR-T cells
- Develop T cell therapy platform and optimize cell-based immunoassays, including ex-vivo antigen-specific T cell isolation and expansion. Multi-color flow cytometry, ELISA, ELISPOT, cytotoxic assays
- Deliver scientific results at internal and external meetings
Requirements
- Hands-on experience and troubleshooting proficiency with immune cell isolation from peripheral blood and leukopak, expansion, and cell based immunoassays
Nice to have
- Experience with TCR-T/CAR-T cells is preferred.
- Extensive knowledge and hands-on experience in TCR-T/CAR-T field.
- Experience in immune-oncology preferred
Skills
- Extensive knowledge and hands-on experience in TCR-T/CAR-T field. Experience in immune-oncology preferred
- Expertise in cell biology and immune cell profiling. Extensive experience in multi-color flow-cytometry
- Experience with dendritic cell culture and DC-T cell cocluture for antigen-specific T cell
- Experience with lentivirus/retrovirus preparation, titration and T cell transduction
- Experience in CRISPR/CAS-9 for gene knock-out and knock-in
- Track record of scientific publications and accomplishments
- Demonstrated ability in presenting scientific results
- Excellent oral and written communication skills
- A team player who can work efficiently as an individual
- Additional Information
- Legend Biotech USA Inc. maintains a drug-free workplace.
Company info
- Company Description
- From the very beginning, we have been focusing on the science.
- We came together as a team of experts, committed to quality, driven by excellence, and dedicated to experimentation.
- Though we faced many challenges, we remained fearless in our research and rigorous in our thinking, pushing ourselves to work harder.
- However, what affected us the most was the enormous burden patient's bear and the difficulties they face, which drove us to think about what's next.
- We believe it is time to accelerate and expand that transformation.
- At Legend Biotech, we are excited to bring clinical trials to patients in our pursuit of a cure.
- While we are focusing on CAR-T in multiple myeloma, we firmly believe the prospects of cellular therapy stretch beyond just one disease or indication.
- The spark of hope is lit.
- At Legend Biotech, we are using that hope to ignite the future of CAR-T cell therapy.
Equal opportunity
- Legend Biotech USA Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce.
Visa & Work Authorization
- ity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protecte
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