10x Genomics
Scientist II, Clinical Bioinformatics
Pleasanton, California, USA HQ · Mid · Full-time
Sponsorship not specified$123k-$167kDetected 26 days ago
AlgorithmsLinuxMachine LearningData AnalysisAI OrchestrationBioinformaticsNGSResearchCommunication
About the role
- 10x Genomics is establishing a diagnostics effort, translating our leading single-cell and spatial assay technologies into impactful clinical applications.
- We are seeking a Scientist II to join the clinical bioinformatics team.
- The successful candidate will have an opportunity to work with some of the largest biomedical datasets assayed using cutting-edge 10x Genomics technologies, deriving clinical insights that power the next generation of clinical diagnostics.
Responsibilities
- Implement rigorous computational/statistical methods for single-cell and spatial transcriptomics data analysis.
- Design, implement and validate biomarkers for diagnostic applications.
- Implement and maintain bioinformatics pipelines for reproducible, large-scale data processing.
- Programming best practices including data analysis reproducibility, version control, design patterns, testing, debugging and profiling
Requirements
- Ph.D. in bioinformatics, computational biology, genomics or a related discipline with extensive hands-on experience in single-cell NGS data analysis.
- A minimum of 2 years of industry experience post Ph.D.
- Experience analyzing large-scale single-cell or spatial transcriptomics datasets to derive biologically meaningful insights and/or diagnostic biomarkers.
- Proficiency working in a Linux environment.
- Hands-on experience with 10x Genomics single-cell and in-situ transcriptomics technologies is a strong preference
- Hands-on research experience in cancer or autoimmune diseases is a strong preference
- Knowledge of clinical genomics, biomarker discovery and diagnostics
- Proficiency with workflow orchestration frameworks such as Snakemake, Nextflow or Martian
Compensation
- $123,400 - $167,000 USD
- About 10x Genomics
- At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.
- We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.
- Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment.
- We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides.
Benefits
- Application of machine learning, particularly in the context of genomics
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