Aralez Bio

Process Development Engineer, Chemistry

Berkeley, CA · Mid · Full-time

Sponsorship not specified$80k-$110kDetected 103 days ago

LogisticsMass SpectrometryCommunicationCollaborationProblem Solving

About the role

We're seeking an experienced Process Development Engineer, Chemistry to join the Process Chemistry and Manufacturing team at Aralez Bio.
This role will be a key, hands-on contributor to the process development, scale-up, and manufacturing operations for the production of a variety of non-canonical amino acids (ncAAs).
The successful candidate will be directly involved in moving processes from the lab-bench scale through pilot runs and into commercial manufacturing.

Set up, operate, monitor, maintain, and troubleshoot manufacturing equipment, including chemical reactors at various scales (10L, 100L, 1000L), filters, pumps, and other equipment and parts.
Maintain raw material & product inventories. Perform container change-outs for products and raw materials including chemicals and solvents.
Perform "scale-up" and "scale-down" procedures for chemical reactions and unit operations, including optimization and troubleshooting, to ensure successful and efficient transfer from lab-scale (milligram to gram) to pilot-scale (kilogram) and eventual manufacturing scale (multi-kilogram to ton).
Maintain quality standards by conducting in-process testing and analysis, using analytical tools such as TLC, HPLC, LCMS, and pH meter, to determine intermediate identity, purity, pH, and concentration.
Participate in ongoing training to develop technical skills and enhance your understanding of chemical manufacturing processes.
Perform preventive and corrective maintenance activities during production downtime. Clean and maintain equipment after production runs.
Ability to consistently follow technical procedures and accurately document all work performed.

You must be able to exert up to 40 lbs of force occasionally, up to 20 lbs of force frequently, and 10 lbs force constantly to move objects.
Required personal safety equipment includes chemically compatible gloves, steel toed shoes, lab coats, face shield, and respirator.
You'll combine your knowledge and experience with creative problem-solving to help optimize the work and improve production processes.
Comfortable but careful: Great precision, attention, and care is required for safety and quality of work.
In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire.

Aralez Bio's salary range for this position is $80,000-$110,000 per year, based on your performance and experience. In addition, your total rewards package will include equity and benefits.
Annual company retreat

Medical / dental / vision insurance coverage
Flexible Spending Account
You are a self-starter who shows up ready to dig in every day with the team, and you're flexible when goals pivot or something goes awry.
Benefits at Aralez Bio

We envision a world where we continuously, sustainably, and affordably improve human life with synthetic biology.
Our proprietary set of enzymes and our manufacturing approach enables the production of thousands of amino acids that were previously too difficult and expensive to make.
These "noncanonical" amino acids that we make are already catalyzing the creation of revolutionary and innovative products that are good for people and the planet.
Our technology outperforms traditional manufacturing approaches by 10-100x across the board.
We already sell products to Big 10 Pharmaceutical companies, and our product family includes the key components of multi-billion dollar blockbuster drugs such as Ozempic and Mounjaro.
We are a diverse, passionate, interdisciplinary team that finds joy in building something new that leaves the world better than we found it.
We strive to always learn and improve and have a deep desire to capitalize on our creativity and be exceptional at what we do.
About the Company

Aralez Bio is an equal opportunity employer and does not discriminate based on race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender, sex, and any other group protected under federal, state, or local laws.
We celebrate diversity and are committed to creating an inclusive environment for all employees.
Please reach out if an accommodation is needed.

This listing is sourced directly from Aralez Bio's careers page and normalized into a canonical job model.