Medra
Scientist, Cell Biology & Antibody Engineering
San Francisco · Mid
Sponsorship not specifiedDetected 176 days ago
RoboticsFlow CytometryCell CultureResearchMass Spectrometry
Stay score
odds of building a lasting career here
37Risky
Cap-exempt (no lottery)0
Sponsors this role80
Entry-level history0
PERM / green-card track0
Lottery odds40
Fits your clock70
Thin sponsorship signal and lottery-bound. A low-probability bet with your clock running. Prioritize cap-exempt roles and proven entry-level sponsors first.
Lottery odds assume a STEM candidate.
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from this employer's Department of Labor filings
Files H-1B transfers
4 transfer filings in the last year, covering 4 workers. Median labor-condition decision: 7 days. An employer that already files transfers is one that can take over an existing H-1B.
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About the role
- Run biophysical characterization on antibody candidates - including SPR and BLI for affinity and kinetics, and epitope binning - and interpret results to inform go/no-go
- Ph.D. in cell biology, immunology, biochemistry, or a related discipline with 2+ years of industry experience, or a B.S./M.S. with 6+ years of deep, hands-on industry experience.
- Strong background in mammalian cell culture and sterile technique, with a track record of maintaining healthy, reproducible cell lines for assay work
Responsibilities
- Design, execute, and interpret antibody screening and characterization campaigns across the full funnel - from high-throughput primary hit triage through orthogonal confirmation
- Develop and run cell-based binding and functional assays using flow cytometry to characterize antibodies, VHHs, and other binder formats
- Maintain and engineer mammalian cell lines (e.g., Expi293, ExpiCHO, HEK293, CHO) and establish cell-based characterization and functional assays
- Partner with roboticists and software engineers to translate manual assay workflows into reliable, high-throughput autonomous protocols on the Medra platform
- Maintain rigorous experimental records in electronic lab notebooks (ELN) and communicate results clearly to internal and external stakeholders
- Deep hands-on expertise in flow cytometry, including high-throughput formats and panel design
- Strong documentation habits, attention to detail, and the ability to drive multiple workstreams in parallel
Requirements
- Experience with alternative binder formats - VHHs, bispecifics, Fc-fusions, ADCs, or non-Ig scaffolds
- Hands-on experience with lab automation and liquid handling platforms
Skills
- Comfort establishing target-overexpressing cell lines and evaluating/implementing new assay technologies
Benefits
- Significant equity ownership
- Medical insurance and dental Insurance
- We offer relocation benefits for applicants who need to relocate.
Company info
- We're a team of passionate, mission-driven engineers and scientists from companies like Tesla, Amazon, SpaceX, and Neuralink. We're collaborative and love moving fast, both with our product and on team trips skiing or go-karting!
- As a team, we love nerding out about engineering and robotics - plus other topics like race cars or cooking. We like learning new things and then sharing our new knowledge with each other.
- Our team is opinionated and straightforward. We don't mind intense discussions about design tradeoffs. If we have arguments or miscommunication, we resolve conflicts quickly and empathetically.
- We're Building:
- At Medra, our mission is to use AI, robotics, and biology to accelerate life science research, with the ultimate goal of eradicating disease.
- We have been quietly building the foundational layers of our
- Physical AI Scientist platform:
- 🤖 Physical AI that can operate scientific instruments with human-level dexterity.
- 🧪 Scientific AI that can analyze results, reason about next steps, and close the loop autonomously.
- This is an incredibly ambitious mission, but we believe that a team of ambitious people with high ownership can accomplish incredible things.
Visa & Work Authorization
- l conditions), sexual orientation, gender identity, gender expression, age, marital status, military or veteran status, citizenship, or other characteristics protected by state, federal or local law or our other policies
This listing is sourced directly from Medra's careers page and normalized into a canonical job model.