NewLimit
Principal/Senior Scientist, PK/PD Assays
South San Francisco · Principal
Sponsorship not specified$155k-$200kDetected 12 days ago
Machine LearningData AnalysisBioinformaticsqPCRCRISPRMolecular BiologyNGSCell CultureResearchProtein AnalysisAnimal Studies
About the role
- About NewLimit NewLimit is a biotechnology company working to radically extend human healthspan.
- We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.
- This Position NewLimit is seeking a Scientist or Senior Scientist with deep expertise in molecular biology, pharmacokinetics and translational biomarker assay development.
Responsibilities
- Own the end-to-end design, development, and qualification of PK and PD biomarker assays across various platforms to support preclinical and IND-enabling studies
- Discover and validate pharmacodynamic biomarkers to support the clinical development of drugs across multiple programs
- Drive data analysis, interpretation, and reporting for bioanalytical studies to support program decision-making with audit-ready data packages
- Mentor research associates, establish SOPs, and build institutional knowledge within the bioanalytical function
Requirements
- PhD in molecular biology, biochemistry, cell biology, or a related field or equivalent industry experience (5+ years)
- Strong working knowledge of bioanalytical method qualification/validation principles for PK/PD biomarker measurements, including familiarity with ICH M10 guidelines and fit-for-purpose frameworks
- Experience with primary cell culture and tissue-derived sample workflows
- NewLimit is seeking a Scientist or Senior Scientist with deep expertise in molecular biology, pharmacokinetics and translational biomarker assay development.
Nice to have
- Track record of bioanalytical method transfer and CRO management for outsourced projects
- Familiarity with preclinical drug development timelines and regulatory submissions (IND, TGA, CTD format)
- Experience with mRNA-LNP biodistribution or nucleic acid-based PK assays
Compensation
- $155,000 to $200,000.
- Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience.
- Learn more at: https://www.newlimit.com/careers *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future.
Benefits
- Comprehensive Health, Dental, and Vision insurance
- Paid parental leave
- NewLimit provides generous benefits so our team can remain focused on our mission:
- Industry-leading PTO: 20 days per year plus holidays
- NewLimit offers a competitive benefits package, which includes a 401k, healthcare coverage, and 20 days of PTO.
Company info
- https://www.newlimit.com/careers *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future.
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