Twenty Twenty Therapeutics

Twenty Twenty Therapeutics

Principal Offensive Cyber Research Engineer

Washington DC · Principal · Full-time

Sponsorship not specifiedDetected 283 days ago
PythonRustC++AWSGCPAzureCloud PlatformsResearchLeadershipCommunication

About the role

  • ABOUT THE COMPANY America is under sustained cyber attack.
  • Our adversaries infiltrate our networks, steal our IP, and degrade the digital infrastructure that modern life runs on.
  • They've learned-correctly-that those attacks rarely produce consequences.

Responsibilities

  • Lead groundbreaking research into advanced adversary behaviors and next-generation offensive cyber techniques.
  • Lead technical governance (e.g., architecture reviews) and provide authoritative guidance on complex decisions.
  • Mentor Staff and Senior engineers, build growth plans, and strengthen the organization's technical leadership bench.
  • Recruit, interview, and assess top-tier offensive cyber talent to build and sustain world-class teams.
  • Lead technical engagements with senior government stakeholders-translating complex capabilities into decision-grade clarity.
  • Build strategic research partnerships across government, academia, and industry to accelerate innovation and impact.

Requirements

  • You have the presence to influence executives and senior government stakeholders without overselling.
  • You have 8-12 years of distinguished experience across offensive cyber operations, advanced research, and software development.
  • You have served in senior technical leadership roles in one or more of: government/military DNEA, Exploitation Analyst (EA) operations, elite red teams, or nation-state threat research.
  • You have defined technical strategy and led large-scale initiatives that shipped durable, high-impact capabilities.
  • You have expert-level understanding of adversary behaviors and TTPs, including deep familiarity with MITRE ATT&CK.
  • You have demonstrated technical judgment in designing complex, scalable systems and establishing engineering standards.
  • You have strong executive and customer communication skills, with experience briefing senior leaders and shaping decisions.
  • You are eligible to obtain a U.S. Government security clearance.

Nice to have

  • You have deployed offensive cyber capabilities into operational use with measurable mission impact.
  • You have a track record of thought leadership through publications, conference talks, or widely respected technical writing.
  • You have deep background in malware development, vulnerability research, or exploit engineering with notable discoveries.
  • You hold advanced technical certifications (e.g., OSEE, GXPN, or equivalent government credentials).
  • You have experience with multi-source intelligence fusion or cross-domain operational environments.
  • You have familiarity with acquisition/requirements processes and guiding capability development across multiple teams.
  • You might work with modern systems programming and scripting languages (e.g., C/C++, Rust, Python).
  • You might work with cloud environments and cloud security across major providers (AWS, Azure, GCP).

Benefits

  • Medical, dental, and vision plan options.
  • Life / AD&D, disability coverage options.
  • Paid parental leave for eligible full-time employees.
  • Paid holidays and flexible PTO.
  • HSA/FSA options, dependent care FSA.
  • Commuter benefits.
  • Building fitness center.
  • Desk setup stipend.
  • We consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, veteran status, disability, or any other protected status.
  • Benefits vary by location, role, and eligibility.

Company info

  • America is under sustained cyber attack.
  • Twenty was founded to change that, by making our adversaries think twice before they attack us.
  • Our vision is American and allied primacy in cyberspace-a future where they cannot contest us, deterrence is assured, and the free world remains secure.
  • Founded in 2024, Twenty Technologies (www.twenty.io http://www.twenty.io) industrializes offensive cyber operations for the U.S. and its allies.
  • Headquartered in Arlington, Virginia, Twenty has raised $138M from Accel, Caffeinated Capital, Friends & Family Capital, Point72 Ventures, General Catalyst, and In-Q-Tel.
  • You will serve as the preeminent technical authority for Twenty's offensive cyber research program-setting the long-term vision, raising the bar on technical execution, and driving breakthroughs in adversary emulation and attack automation.
  • Your work will shape how we build and standardize offensive capabilities that support real-world national security outcomes.
  • You'll partner closely with engineering, product, and operations leaders, and you'll regularly advise executive leadership and government stakeholders on strategy, technical risk, and capability evolution.

Equal opportunity

  • equal opportunity employer.
  • If you need a reasonable accommodation during the hiring process, let us know and we will work with you.

Visa & Work Authorization

  • Government security clearance
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