Sail Biomedicines
Research Associate II, Preclinical Manufacturing
Cambridge, MA · Mid
Sponsorship not specified$75k-$100kDetected 15 days ago
Data AnalysisClinical Laboratory TechniquesPCRMolecular BiologyResearchExperimental DesignMass SpectrometryAnimal Studies
About the role
- Sail Biomedicines is seeking a Research Associate II to join our Preclinical Manufacturing team, supporting the production of RNA and lipid nanoparticle (LNP) drug substances and drug products.
- As part of the Technical Operations group, you will contribute directly to the development and delivery of preclinical materials for both internal and partnered programs.
- Thisis a hands-on, lab-based role requiring strong experimental execution, attention to detail, and cross-functional collaboration.
Responsibilities
- Support the production of RNA cargo molecules and lipid nanoparticle (LNP) formulations for preclinical studies
- Operate and maintain lab-scale instrumentation, including AKTA (FPLC), TFF systems, PCR, HPLC, capillary electrophoresis, UV-Vis, and light scattering platforms
- Perform analytical characterization and quantification of RNA and other nucleic acids
- Analyze experimental data and document results in electronic lab notebooks (ELN) and technical reports
- Collaborate cross-functionally with research, analytical, and process development teams to support project goals
- Sail Biomedicines is pioneering the integrative design and deployment of fully programmable medicines to transform patient care.
- By leveraging cutting-edge eRNA and nanoparticle deployment technology, Sail is also making unparalleled use of AI techniques to identify and design fully programmable medicines that are potent, targeted, versatile, and tunable.
Requirements
- B.S. with 2+ years of industry experience or M.S. in Molecular Biology, Biochemistry, Biochemical Engineering, or a related field
- Hands-on experience in one or more of the following areas:
Nice to have
- Detail-oriented with strong organizational and documentation skills
- Curious, proactive, and comfortable working both independently and in collaborative environments
- Effective communicator with the ability to clearly present technical data and insights
- RNA/DNA production and purification
- LNP formulation and characterization
- Chromatography (e.g., AKTA/FPLC, HPLC)
- Tangential flow filtration (TFF)
- Automated liquid handling systems
Compensation
- $75,000 - $100,000
Company info
- Sail was founded by Flagship Pioneering.
Equal opportunity
- Sail Biomedicines is an Equal Opportunity Employer.
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