GRAIL

GRAIL

Staff Software Engineer – Data Team #4555

Sunnyvale, CA · Staff+ · Full-time

Sponsorship not specified$169k-$224kDetected 90 days ago
PythonGoSQLGCPAPI DevelopmentData EngineeringData ScienceIncident ResponseComplianceHIPAAClinical TrialsClinical ResearchFDA RegulatoryBioinformaticsNGSResearchLab ResearchCollaborationGxP

Stay score

odds of building a lasting career here

61Sponsors, lottery-bound
Cap-exempt (no lottery)0
Sponsors this role90
Entry-level history0
PERM / green-card track0
Lottery odds (Level IV)94
Fits your clock70

Sponsors, but it's cap-subject — you still face the weighted lottery (~61% per draw at Level IV). Good if you win; have a cap-exempt backup on your list.

Lottery odds assume a STEM candidate.

Personalize to your clock →

H-1B wage level

the lottery is wage-weighted — each level is one more entry

Level I · 1×
Level I$152,7971 entry
Level II$187,0752 entries
Level III$221,3743 entries
Level IV$255,6534 entries

$18,075 more — $187,075 — moves this role to Level II and 2 lottery entries. That figure is inside the range the employer already advertised.

Based on the DOL prevailing wage for this occupation and worksite, a base salary of $187,075 would place this position at wage Level II. That figure is within the posted range, and I'd like to target it. This role classifies under "Software Developers" for prevailing-wage purposes.

DOL prevailing wage, 2026-27 wage year · Software Developers (15-1252) · San Jose-Sunnyvale-Santa Clara, CA. Wage level is derived by USCIS from the offered wage, occupation and worksite; the occupation shown is inferred from the job title.

Employer immigration record

from this employer's Department of Labor filings

Files H-1B transfers

5 transfer filings in the last year, covering 5 workers. Median labor-condition decision: 7 days. An employer that already files transfers is one that can take over an existing H-1B.

Sourced from Department of Labor LCA, PERM and prevailing-wage disclosure data. Employer matching is by name, so figures may be split across an employer's legal entities. Absence of a filing means none appears in our copy of the data, not that none exists.

Community outcomes

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About the role

  • GRAIL is headquartered in the Bay Area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom.
  • It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
  • For more information, please visit grail.com GRAIL is seeking a Staff Software Engineer for the Data Team.

Responsibilities

  • Design and implement software systems that turn raw clinical, lab, and operational data into reliable, analysis-ready datasets
  • Partner with scientists, clinicians, lab operations, and data teams to understand data generation, transformation, and usage needs
  • Develop services, libraries, data models, and workflow components that enforce data integrity, access control, and compliance by design
  • Collaborate on cross-functional initiatives involving data quality, testing strategy, monitoring, and operational excellence
  • Lead software engineering efforts for long-lived systems that must evolve alongside active clinical and research programs
  • Mentor engineers and collaborate with scientists to ensure software decisions support both technical and scientific outcomes
  • Contribute to documentation, onboarding materials, and processes that support cross-functional adoption and data literacy across teams
  • Strong software engineering fundamentals, including system design, data modeling, API design, and writing well-tested production code.
  • Experience building and operating data-intensive software systems, not just declarative pipelines or SQL-only workflows
  • GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow.

Requirements

  • 7+ years of experience building production-grade software systems
  • Proficiency in Go or Python (or similar general-purpose language)
  • Experience with data modeling, validation, and transforming real-world data into usable formats
  • BS in Computer Science, Engineering or Bioinformatics, or a related field, or equivalent practical experience

Nice to have

  • 2+ years experience working in regulated or clinical data environments (e.g., HIPAA, CLIA, GCP, FDA compliance)
  • Direct experience working with or supporting scientific teams (e.g., bioinformatics, wet lab, clinical research)
  • Prior experience working in biotech, diagnostics, or life sciences companies
  • Experience supporting sample tracking, structured scientific data pipelines, or cross-functional data lifecycle management
  • Experience designing systems with data sequestration, permissioning, or privacy controls
  • Experience writing or contributing to software libraries, shared tooling, or reusable components used by other teams
  • Advanced degree (MS or PhD) in computer science, engineering, bioinformatics or a related discipline
  • Familiarity with GxP practices and regulatory reporting requirements in clinical studies is a plus

Compensation

  • The expected, full-time, annual base pay scale for this position is $169k-$224k.

Benefits

  • We are a healthcare company, pioneering new technologies to advance early cancer detection.

Company info

  • Our mission is to detect cancer early, when it can be cured.
  • We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

Equal opportunity

  • Please contact us at rc@grailbio.com if you require an accommodation to apply for an open position.

This listing is sourced directly from GRAIL's careers page and normalized into a canonical job model.