Vaxcyte

Scientist II, Conjugation Development

San Carlos, California, United States · Mid

Sponsorship not specified$146k-$171kDetected 34 days ago

Process ImprovementResearchExperimental DesignMass SpectrometryCommunicationCollaborationOrganizational Skills

About the role

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked.
Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning.
Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.

The candidate's primary responsibility will be to lead and execute experimental activities that support company's pneumococcal conjugate vaccine program with a focus on developing a deeper understanding of the conjugation process.
The successful candidate will be expected to design, execute, and troubleshoot experiments with minimal guidance.
Optimize and troubleshoot multi-step syntheses of protein-polysaccharide conjugates.
Analyze polysaccharides and conjugates with a variety of analytical methods. Develop new laboratory workflows and analyses beyond established procedures when appropriate.
Advise team members on experimental design, interpretation of results, and troubleshooting.
Maintain highly organized records to enable optimization and assessment of reproducibility.

PhD in chemistry, biochemistry, or related field with minimum 2-5 years of industry experience, or combination of industry and postdoctoral research
MS with minimum 7 years industry experience, or BS with minimum 10 years of industry experience.
Proficiency with small- and large-scale techniques for purification of bioconjugates, including tangential flow filtration.
Proficiency in a variety of techniques for bioconjugate analysis such as colorimetric assays, HPLC, and SEC-MALS.
Experience with Design of Experiments is desirable.
Experience with chemical modification of polysaccharides is desirable.
Experience implementing and/or using electronic notebooks is desirable.
ability to communicate effectively both verbally and in written formats.
Enthusiasm to learn the new skills and techniques necessary to tackle problems outside of current area of expertise.

$146,000 - $171,000
The compensation package will be competitive and includes comprehensive benefits and an equity component.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.

This listing is sourced directly from Vaxcyte's careers page and normalized into a canonical job model.