structuretx

VP, Global Manufacturing and Supply Chain

South San Francisco, California · Vp

Sponsorship not specified$300k-$390kDetected 20 days ago

Business DevelopmentForecastingSupply ChainLogisticsCadenceClinical TrialsGMPLeadershipCommunicationCollaborationDemand PlanningProcurement

About the role

This role requires deep expertise in small molecule pharmaceutical operations, an understanding of the pharmaceutical product development lifecycle, excellent business acumen and the ability to thrive in a dynamic, fast-paced environment.
Excellent communication skills are a must for this multidisciplinary and global effort.

Responsibilities

Develop and lead the external manufacturing strategy across DS, DP, and packaged/finished product to support global clinical trials and commercial supply.
Lead CDMO governance and relationship management, including executive-level interactions, KPIs, and escalation pathways.
Partner with Quality and Regulatory to ensure GMP compliance, inspection readiness, and alignment with global regulatory expectations.
Collaborate cross-functionally with CMC Development, Quality, Supply Chain, and Regulatory to align on technical transfers, validation strategies, and lifecycle management.
Proactively identify risks and implement mitigation plans to ensure continuity and robustness of external manufacturing operations.
Provide strategic input into make/buy decisions, site selection, and future-state network design.
Support business development and sourcing efforts related to manufacturing.
Lead CDMO strategic sourcing and selection efforts from needs definition to RFP to selection and start-up to secure the necessary CDMO capabilities and capacities to meet all product supply needs.
Direct global demand forecasting, supply planning, and inventory strategies to support clinical and commercial needs.
Lead commercial launch execution activities within Tech Ops.

Requirements

20+ years of progressive leadership experience in biopharmaceutical manufacturing, supply chain, technical operations with at least 5+ years' experience in external CDMO management.
Experience with small molecule API manufacturing, oral solid dosage forms and combination products.
Deep understanding of GMP, GDP, and international regulatory requirements, with launch readiness experience in the U.S. and EU markets.
Excellent business acumen and demonstrated ability to think strategically and ensure excellence in execution in complex programs operation under tight timelines and budgets.
Ability to influence internal and external stakeholders.
Travel Required: Up to 30%
Proven success in building or scaling manufacturing and supply chain teams and leading new product launches.
Deep understanding of GMP compliance, Regulatory CMC expectations and global supply chain requirements.
Excellent leadership, communication, and cross-functional collaboration skills. Ability to influence internal and external stakeholders.
Partnership mindset and ability to build relationships with key partners in Quality, Regulatory, CMC, Technical Operations, R&D and Commercial functions.
Demonstrated success in building scalable teams, leading complex projects and driving accountability in matrixed organizations
Structure Therapeutics Inc. is an Equal-Opportunity Employer.
Structure Therapeutics is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is $300,000 - $390,000 The exact base pay offered for this role will depend on various factors, including but not limited to the candidate's geography, qualifications, skills, and experience.
At Structure, base pay is only one part of your total compensation package. The successful candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance-based equity. Structure Therapeutics also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, unlimited PTO, and a number of paid holidays including winter shutdown.

Nice to have

Minimum bachelor's degree in supply chain, Engineering, or related field (MBA preferred).

Compensation

Structure Therapeutics is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive.

Benefits

The successful candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance-based equity.
Structure Therapeutics also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, unlimited PTO, and a number of paid holidays including winter shutdown.

Company info

Structure Therapeutics is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive.
At Structure, base pay is only one part of your total compensation package.

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