Deeporigin
Senior Scientific Developer
United States · Senior
No sponsorshipDetected 13 days ago
JavaScriptTypeScriptPythonBackend DevelopmentFull-Stack DevelopmentAlgorithmsCode ReviewPostgreSQLDockerKubernetesCI/CDPlatform EngineeringAI OrchestrationBioinformaticsResearchProblem Solving
About the role
- This is a hands-on role at the intersection of scientific computing and software engineering.
- You will work across our Python SDK, scientific workflow definitions, containerized compute functions, and the Julia packages that power our molecular simulation stack.
- Deep domain knowledge in at least one of: medicinal chemistry, cheminformatics, structural biology, molecular simulation, or computational drug discovery.
Responsibilities
- You will have ownership of key scientific capabilities from design through deployment, with a high level of independence and direct impact on what researchers can run on the platform.
- Design, implement, and maintain scientific software for drug discovery: docking, free-energy perturbation (FEP), molecular dynamics, cheminformatics, and related computational biology workflows.
- Build and evolve the Deep Origin Python SDK and scientific APIs that scientists use to run, monitor, and analyze platform workflows.
- Develop and maintain Julia-based simulation and analysis packages for molecular systems (e.g., system preparation, MD/FEP protocols, post-processing).
Requirements
- MSc or PhD in chemistry, chemical biology, bioinformatics, computational chemistry, or a closely related field - or equivalent industry experience with a strong scientific track record.
- You know how to containerize Python scripts, packages, and dependencies into reliable images.
Nice to have
- TypeScript/JavaScript experience - our platform UI and some backend services use modern web stacks.
- Experience with PostgreSQL or scientific data platforms (chemical structure storage, RDKit, etc.).
- Contributions to open-source scientific software.
- Experience at an early-stage startup shipping scientific product features quickly.
- Values & Working Style Scientific rigor meets engineering pragmatism - you care about correctness and reproducibility, but you ship.
- Comfortable with ambiguity - you can navigate underspecified scientific requirements and help define the right scope.
- Curious and self-directed - you learn new domains (chemistry, infra, workflows) as the product demands.
- Why This Role Matters Now As we scale our AI-driven drug discovery platform, the quality and breadth of our scientific compute stack directly determines what researchers can discover and how fast they can iterate.
Skills
- medicinal chemistry, cheminformatics, structural biology, molecular simulation, or computational drug discovery.
- docking, free-energy perturbation (FEP), molecular dynamics, cheminformatics, and related computational biology workflows.
- Package scientific tools as reproducible, containerized functions with clear input/output contracts, validation, and integration tests.
- Translate domain requirements from medicinal chemistry and computational biology into robust, scalable technical implementations.
- Debug and resolve issues across the full stack - from numerical methods and force-field behavior to workflow failures in production.
Compensation
- Annual team gatherings and company events.
Benefits
- Opportunity to shape the future of health, longevity, and our ability to simulate life.
- Competitive compensation package with meaningful equity.
- Comprehensive health, dental, and vision coverage.
- Free lunch, snacks, beverages, and onsite gym access (for in-office employees).
Company info
- Deep Origin is a biotech startup building an operating system for science that transforms how life science research is conducted.
- Led by Michael Antonov, co-founder of Oculus, and backed by Formic Ventures, we are redefining the infrastructure behind modern drug discovery.
- Our AI-driven platform enables scientists to accelerate discovery, reduce cost, and bring breakthrough innovations to life faster.
- As we scale, engineering excellence is a critical lever in advancing our mission to dramatically reduce disease and extend human healthspan.
- We are hiring a Senior Scientific Developer to help build and scale the computational science layer of our drug discovery platform.
Visa & Work Authorization
- Applicants must be authorized to work for any employer in the U
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This listing is sourced directly from Deeporigin's careers page and normalized into a canonical job model.