Nurix Therapeutics
Senior Director, Quality Control
Brisbane, California, United States · Director
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About the role
- Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine's next chapter with a new script to outmatch disease.
- Position Description Nurix Therapeutics is seeking an experienced Senior Director, Quality Control to join the Analytical Development and Quality Control group.
- The ideal candidate brings deep expertise in small molecule QC, strong regulatory acumen, and proven experience managing external CDMO and CTL relationships.
Responsibilities
- Build and lead the QC function: Establish QC systems and infrastructure
- recruit, manage, and mentor internal QC staff and contractors
- Identify and manage quality risk: Proactively identify, assess, and escalate risks related to patient safety, product quality, shelf life, supply continuity, or GMP compliance
- drive risk mitigation strategies in partnership with Analytical Development, Quality, and Manufacturing functions
- collaborate with Quality to conduct audits of GMP manufacturing and testing sites, including CDMOs and CTLs
- Direct stability programs: Develop and execute stability strategy in collaboration with Analytical Development leads, ensuring alignment with ICH guidelines and regional regulatory requirements
- Manage reference materials and retains: Oversee qualification and inventory of reference standards
- develop sampling plans and manage sample retain programs
- Drive continuous improvement: Identify and implement process improvements, data integrity enhancements, and quality system upgrades (e.g., eQMS) to support a scalable, inspection-ready QC organization
- Build and lead the QC function: Establish QC systems and infrastructure; recruit, manage, and mentor internal QC staff and contractors
Requirements
- Advanced degree in Chemistry, Pharmaceutics, Chemical Engineering, or related discipline.
- BS/MS with 16+ years of relevant experience, or PhD with 14+ years of relevant experience
- Deep experience in small molecule pharmaceutical development, including method lifecycle management and oversight of validation, release, and stability operations
- Proven experience managing external manufacturing and testing operations at CDMOs and CTLs
- Expertise with analytical methods such as HPLC, GC, dissolution, and microbiological testing
- Deep working knowledge of cGMP, ICH guidelines, and USP/EP/JP compendial standards
- Advanced degree in Chemistry, Pharmaceutics, Chemical Engineering, or related discipline. BS/MS with 16+ years of relevant experience, or PhD with 14+ years of relevant experience
- 5+ years in a QC leadership or management role, with demonstrated ability to build and mentor teams
- Direct experience leading through health authority inspections and internal audits and conducting audits of manufacturing and testing sites.
- Experience contributing to global regulatory filings and health authority correspondence (e.g., responses to information requests, post-approval changes)
- Strong interpersonal and cross-functional collaboration skills, with the ability to influence and build consensus across Quality, Supply Chain, Analytical Development, and Manufacturing functions
- Strong team orientation; highly collaborative
- Solutions and results-oriented focus
- Hands-on approach; resourceful and open to diverse points of view
Compensation
- $280,200 - $319,800
Benefits
- Lead QC through audits and inspections: Serve as QC lead during health authority inspections and internal audits
- Support regulatory submissions and health authority interactions: Contribute to global regulatory filings
- collaborate on responses to health authority information requests, regulatory commitments, and post-approval changes
This listing is sourced directly from Nurix Therapeutics's careers page and normalized into a canonical job model.