BillionToOne
Senior Director, Software Product Management and Product Engineering
Menlo Park, CA · Director
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odds of building a lasting career here
Sponsors, but it's cap-subject — you still face the weighted lottery (~61% per draw at Level IV). Good if you win; have a cap-exempt backup on your list.
Lottery odds assume a STEM candidate.
Personalize to your clock →H-1B wage level
the lottery is wage-weighted — each level is one more entry
This range already reaches Level IV — the maximum four lottery entries.
DOL prevailing wage, 2026-27 wage year · Computer Occupations, All Other (15-1299) · San Francisco-Oakland-Fremont, CA. Wage level is derived by USCIS from the offered wage, occupation and worksite; the occupation shown is inferred from the job title.
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About the role
- A Rare Opportunity to Shape the Future of Genomics Join a team of brilliant, passionate innovators determined to transform healthcare.
- Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics.
- This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
Responsibilities
- Lead and manage the Software Product Management and Software Product Engineering organizations across oncology and prenatal software products
- Drive an AI-first approach across both product development and engineering operations, leveraging modern AI technologies and tools to accelerate development and improve software quality and team productivity
- Partner closely with Clinical Product, Data Science, Bioinformatics, IT/IS, Operations, and Commercial teams to deliver category-defining software experiences and operational platforms
- Lead engineering managers and software engineering teams responsible for architecture, development, infrastructure, quality, scalability, and operational excellence
- Build a high-performance culture centered around customer obsession, ownership, speed, technical excellence, and business impact
Requirements
- 10+ years of experience in software product management, software engineering, or technology leadership roles with increasing organizational responsibility
- Experience managing software engineering organizations and engineering leaders
- Strong understanding of software architecture, platform development, system scalability, and engineering tradeoffs
- Strong product instincts with the ability to identify and translate emerging technologies into practical customer-facing solutions
- Highly entrepreneurial mindset with the ability to operate strategically while remaining hands-on when needed
- Experience operating in fast-paced, high-growth environments with ambiguity and rapid iteration
- Strong product management background with demonstrated end-to-end ownership of complex software products and platforms
- Proven ability to lead both product and engineering functions simultaneously
- Track record of building and scaling customer-facing software products and/or complex operational software systems
- Experience leveraging AI technologies and AI-enabled development workflows to deliver customer and business value
- Excellent leadership, communication, and cross-functional collaboration skills
- Experience in healthcare, diagnostics, life sciences, genomics, or regulated environments
- Experience building provider-facing or patient-facing healthcare software products
- Strong experience with US healthcare technologies and ecosystems, including healthcare data, interoperability standards, and clinical workflow systems
Compensation
- Cost-of-living adjustments to your base salary twice per year
- The base salary range for this role is $261,102 - $304,619.
Benefits
- Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
- Extremely generous Family Bonding Leave for eligible employees (16 weeks, paid at 100%)
- Supplemental fertility benefits coverage
- Retirement savings program including a 4% Company match
- Increase paid time off with increased tenure
- This position is eligible for an annual bonus and receives a new hire equity grant of up to $260,000 at grant value, vesting over four years, plus annual equity refresh grants equal in value to the new hire grant.
- Together, the total four-year value of base, target bonus, and equity is up to approximately $2.0 million.
Company info
- We are seeking a highly driven leader for one of the most critical and high-impact roles at BillionToOne: the Senior Director of Software Product Management & Product Engineering.
This listing is sourced directly from BillionToOne's careers page and normalized into a canonical job model.