Kingdom Industry
Senior Scientist, Computational Biology & Data Infrastructure
Brooklyn, NY · Senior · Full-time
Sponsorship not specified$133k-$160kDetected 37 days ago
PythonCode ReviewSQLLLMsStatisticsCadenceClinical TrialsBioinformaticsResearchExperimental DesignCommunication
About the role
- We've pioneered Superculture® ingredients: an entirely new class of clinically validated postbiotics, made from natural microbes, that target the root causes of unmet health needs for people and pets.
- We're launching one new clinically backed ingredient every year.
- We're looking for a high-performing Senior Scientist, Computational Biology & Data Infrastructure, to join our small but mighty team.
Responsibilities
- Own genomic analyses and biobank strategy:
- Maintain the whole-genome sequencing pipeline: assembly of incoming sequencing data, linkage of genomes to strain records, and curation of best-available assemblies for downstream use
- Own and operate the strain dereplication pipeline, advancing isolated colonies from primary 16S/ITS screening through unique-strain identification and entry into the biobank
- Design and curate screening plates for downstream functional assays, including layout, strain selection, and verification of taxonomy and safety annotations
- Build and own Kingdom's AI-compatible scientific data infrastructure:
- Build AI-compatible data infrastructure for Kingdom that captures, stores, and analyzes data across a variety of modalities
- Develop and apply statistical and computational methods to power biological insights and support wet-lab workflows, including experimental design, metric development and validation, and method onboarding, powered with new AI/agentic tools
- Maintain the integrity of the strain database backend: tube tracking, naming conventions, and audits of our physical inventory and pipeline data to identify anomalies
- Scope, build, and ship the data processing, analysis, and metrics that give new assays clear, validated benchmarks
- AI-native: daily Claude Code or equivalent use, prompt fluency, comfort rebuilding research cadence around agentic tools, with experience building tooling around your own research
Requirements
- ~1-3 years post-PhD
- Strong knowledge of statistics and quantitative methods
- proficiency modeling complex interrelated entities and comfort establishing and communicating an ontology
- Experience designing and maintaining bio-data infrastructure: proficiency modeling complex interrelated entities and comfort establishing and communicating an ontology
- PhD (or equivalent depth) in computational biology, bioinformatics, microbial genomics, or a related quantitative life-sciences field; ~1-3 years post-PhD
Compensation
- $132.5K-$160K).
- Fully stocked kitchen with fruits, snacks, and beverages + weekly team lunches
- 401k program with minimal fees
Benefits
- 100% fully-covered, best-in-class medical, vision, and dental insurance for yourself (and 95% for your spouse/family)
- Generous and flexible PTO, in addition to 13 company-wide holidays
- Full commuter coverage
- 12-weeks fully-paid parental leave
- High agency: self-starter who identifies pain points, proposes a plan and solution, and drives their own learning
- Growth and learning: Kingdom's scientific AI and data-infrastructure function is still being defined, so you'll have real influence over what it becomes.
- We hold one another to high standards, but do so while being deeply committed to each other's wellbeing.
- Kingdom additionally offers an excellent benefits package including:
- This does not include stock options, which we'll discuss during the interview process.
Company info
- contribute to a category-defining biotech company at the frontier of postbiotic science.
- Solve from first principles. We have a deep-seated curiosity about the most important problems facing the business. Our nature is to dig deeply into their details, question assumptions, understand the smallest details, and drive towards the best possible solution using these insights. This makes us very effective in crafting new solutions and operating in ambiguous circumstances.
- Collaborate with kindness. We are exceptionally low ego, and treat each other with respect, compassion, and humility. We hold one another to high standards, but do so while being deeply committed to each other's wellbeing. We invest in each other's growth, and are willing to engage in difficult conversations and deliver direct, constructive feedback when necessary.
- Be resourceful and resilient. We figure out how to make things work, and how to accomplish our goals regardless of what stands in the way. We're keen to confront challenges together through proactive planning and scrappy methods. When things go wrong, we learn quickly from our missteps, adapt our approach, and push forward.
- Kingdom is building the world's first AI-native functional ingredients company, with $40M+ in venture funding from top investors.
- One in three product launches using our ingredients has earned a #1 New Release on Amazon, and nine in ten of our customers are launching additional products with us.
- We are exceptionally low ego, and treat each other with respect, compassion, and humility.
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