Allegro
Principal Scientist, Biosensor Assay Development
Manchester, NH · Principal
Sponsorship not specifiedDetected 31 days ago
Customer SuccessMolecular BiologyLeadership
About the role
- This is a foundational role within a specialized internal venture, where you will be responsible for the "wet-ware" and surface chemistry that allows our sensors to interface with complex biological systems.
- As a hands-on leader, you will establish our Manchester-based biochemistry lab, oversee the development of diverse assay formats, and work directly with global customers to transition their biological and diagnostic applications onto our sensing platform.
Responsibilities
- Foundational Lab Leadership: Establish and oversee a new biochemistry R&D laboratory in Manchester. You will define SOPs, manage safety protocols, and lead a small, agile team (initially 1-2 members) to support rapid prototyping and validation.
- Multi-Modal Assay Development: Lead the design and optimization of various assay formats, including sandwich and competitive architectures.
- Surface Chemistry & Interface Engineering: Optimize the functionalization of sensor surfaces.
- You will develop robust protocols for tethering capture molecules to semiconductor-based sensor stacks while minimizing non-specific binding and ensuring long-term reagent stability.
- Field Applications & Customer Success: Serve as the Lead Field Applications Scientist (FAS).
- Production & Method Transfer: Collaborate with microfluidic, packaging, and manufacturing engineers to ensure biochemical methods are compatible with high-volume production and cartridge assembly processes.
- Ability to travel up to 25% to support global customer integration and production bring-up.
- You will define SOPs, manage safety protocols, and lead a small, agile team (initially 1-2 members) to support rapid prototyping and validation.
- We foster a culture of Real Innovation, empowering you to push boundaries, develop cutting-edge solutions, and drive continuous improvement.
- Your work will create a Real Impact by solving complex real-world challenges that fuel our success and shape the future of technology.
Requirements
- 8-12 years of experience in Assay Development within the diagnostics or life sciences industry.
- Proven success in taking an assay from early-stage concept through to a validated method.
- Deep expertise in immunoassays and/or molecular diagnostic techniques.
- Strong understanding of surface functionalization (e.g., silanes, PEGylation, or related chemistry).
- Experience working with microfluidic systems or "Lab-on-a-Chip" platforms.
- You must be comfortable wearing many hats-from bench work and lab management to technical sales support and high-level strategy.
- Ability to bridge the gap between biochemistry and electronic engineering.
Benefits
- A "hands-on" entrepreneurial approach.
Company info
- We are seeking a Principal Assay Scientist to lead the biochemical development and application of our Giant Magnetoresistance (GMR) biosensor platform.
- You will support early-adopter customers by creating proof-of-concept samples, validating their specific use cases, and traveling to customer sites to assist with technical bring-up and method transfer.
- Join Allegro and become part of a team where your contributions truly matter.
- At Allegro, we are committed to providing a harassment-free environment of mutual respect to fuel innovation through inclusive thought collaboration.
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