Kiniksapharmaceuticals

Director, New Target Strategy

Lexington, MA · Director

Sponsorship not specified$215k-$250kDetected 22 days ago

Business DevelopmentPharmacologyFDA RegulatoryBioinformaticsResearchAnimal StudiesLeadership

About the role

Grounded in rigorous science and bold innovation, the company fosters a highly collaborative, patient‑first culture led by accomplished life sciences leaders.
At Kiniksa, talented individuals are trusted and empowered to make a real impact-shaping the future of medicine while improving the lives of patients who need it most.
The role reports to Group Vice President, Chief Business Officer.

Responsibilities

Lead identification and prioritization of novel therapeutic targets using information such as human genetics, functional genomics, emerging disease biology and clinical data.
Serve as a scientific lead for internal and external diligence activities related to new targets, platforms, non-clinical- and early clinical-stage assets, critically assess biological plausibility, differentiation, feasibility, and risk of potential targets and programs and prepare and present clear, data driven recommendations to senior busine ss development and research leadership.
Design target validation strategies incorporating in vitro, in vivo, and ex vivo approaches ensuring development of high‑quality biological data packages to support progression into lead candidate development, collaborating closely with chemistry, biologics, and platform teams to align biology with modality and development strategy.
Strategic Scientific Diligence & Portfolio Judgment - Rigorously evaluating early-stage assets and platforms, balancing biological rationale, differentiation, and risk to drive confident investment and partnering decisions.
Willingness and curiosity to learn and implement emerging AI tools to drive efficiency.
Kiniksa Pharmaceuticals is a commercial‑stage biopharmaceutical company developing and commercializing novel therapies for diseases with unmet need, with a focus on cardiovascular indications.
With deep expertise in immunology and inflammation, Kiniksa is advancing a growing portfolio of approved and investigational medicines, anchored by its lead product, ARCALYST®, the first and only FDA‑approved therapy for recurrent pericarditis.
Kiniksa is seeking a highly motivated and scientifically rigorous Director, New Target Strategy to lead and contribute to early discovery efforts within the Business Development organization.
This role will play a critical leadership position in target identification, scientific diligence, and target validation, helping to evaluate, build, and advance a robust and differentiated portfolio through internal discovery and external business development activities in rare, cardiovascular and inflammatory diseases.

Requirements

Experience leading or contributing to scientific diligence activities for internal pipeline programs and external opportunities.

Skills

Translating Human Biology into High-Value Targets
Strategic Scientific Diligence & Portfolio Judgment
End-to-End Target Validation Leadership
Patient-Centered Drive & Entrepreneurial Energy

Compensation

$215,000 - $250,000 USD
Kiniksa does not accept unsolicited resumes from staffing agencies or search firms. Any resumes submitted without a signed agreement will be considered property of Kiniksa, and no fees will be paid.

Benefits

Contribute to portfolio strategy by evaluating disease mechanisms, competitive landscapes, and unmet medical needs and drive hypothesis generation grounded in human disease relevance and translational potential.
Compensation decisions are based on objective criteria including role responsibilities, experience/qualifications, internal equity, geographic location, and external market benchmarks.
decisions are based on objective criteria including role responsibilities, experience/qualifications, internal equity, geographic location, and external market benchmarks.

Equal opportunity

Please contact us to request accommodation.

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