Simons Foundation

Simons Foundation

Senior Software Engineer, Genomics

162 Fifth Avenue, New York, NY · Senior · Full-time

Sponsorship not specified$160k-$200kDetected 34 days ago
PythonCode ReviewPostgreSQLMySQLAWSCloud PlatformsDockerKubernetesCI/CDMachine LearningPyTorchscikit-learnData EngineeringBioinformaticsResearchCommunicationCollaboration

About the role

  • This is a high-impact role that directly advances the study of human genomics and disease.
  • This is a hands-on backend role for an experienced engineer with expertise in biological data, genomics, and -omics technologies.
  • They will also have experience processing large-scale -omics datasets, maintaining production software systems, designing and optimizing data-intensive pipelines, and supporting machine learning workflows in scientific computing environments.

Responsibilities

  • Contribute to the design, architecture, and implementation of new HumanBase features and major infrastructure improvements
  • Design, develop, and optimize scalable genomics and biomedical data processing pipelines that ingest, normalize, and transform heterogeneous datasets
  • Collaborate closely with computational biologists, data scientists, and external partners to align engineering efforts with scientific and platform goals
  • Contribute to operational support, maintenance, and continuous improvement of production systems supporting HumanBase
  • The Center for Computational Biology (CCB) is seeking an experienced senior software engineer to join a growing team of developers within CCB and the other centers across the Flatiron Institute who help build and maintain HumanBase.

Requirements

  • At least 8 years of professional software engineering experience, including work on production systems and data-intensive applications
  • Extensive experience with Python, including development of complex data pipelines and use of applicable software libraries
  • Strong experience with relational databases such as PostgreSQL or MySQL, including schema design and query optimization
  • Experience with containerization and cloud-native infrastructure technologies such as Docker and Kubernetes
  • Demonstrated experience with the full software development lifecycle (SDLC), including testing, CI/CD, version control, and deployment
  • Excellent communication skills, with the ability to engage technical and non-technical audiences, including senior leadership.
  • Strong cross-functional collaboration skills, with a track record of working effectively with non-engineering stakeholders to translate needs into software solutions.
  • Perform other duties or tasks as assigned or required

Nice to have

  • Advanced degree in Computer Science, Engineering, Bioinformatics, or a related field.
  • Expertise in bioinformatics, including experience with genomic data processing, analysis pipelines, and related computational methods.
  • Familiarity with AWS or other major cloud platforms.
  • Experience with high-performance computing (HPC) environments.
  • Please submit a résumé and cover letter stating your interest in the position.
  • Our Commitment to Expanding Pathways to Science & Opportunities for All:
  • Many of the greatest ideas and discoveries come from a diverse mix of minds, backgrounds, and experiences.
  • Experience working with large, heterogeneous biological datasets in Python (HDF5, Parquet, PyArrow, xarray ) -ideally in genomics or biomedical contexts

Skills

  • Related Skills & Other Requirements

Compensation

  • The full-time annual compensation range for this position is $ 160,000-$200,000 depending on experience.

Benefits

  • In addition to competitive salaries, the Simons Foundation provides employees with an outstanding benefits package.
  • Integrate machine learning and statistical methods into production workflows for analysis of complex biological datasets
  • The Simons Foundation is committed to advancing basic science and mathematics to benefit humankind and expand our collective understanding of our world.

Company info

  • As part of our mission, we support partners, programs, and initiatives that seek to broaden the scientific community and open pathways to science and mathematics careers.

This listing is sourced directly from Simons Foundation's careers page and normalized into a canonical job model.