Neurocrine

Neurocrine

Exec Director, API Synthetic Development

US CA San Diego · Director

Sponsorship not specified$244k-$333kDetected 7 days ago
API DevelopmentA/B TestingNegotiationGMPFDA RegulatoryResearchAnimal StudiesLeadershipCommunicationCollaboration

About the role

  • Independently conducts synthesis and process development activities for preclinical and clinical candidates, including laboratory experimentation for compound preparation.
  • Works on challenges of significant scope in which analysis of situation or data requires executive review and discussion. _
  • Your Contributions (include, but are not limited to):

Responsibilities

  • Directs the route selection, design, and scale-up of pharmaceutical ingredient (API) processes - inclusive of instruments and equipment - from the laboratory through pilot and manufacturing scale.
  • Directs the design and scale-up of processes, instruments and equipment from the laboratory through pilot plant and manufacturing scale-up
  • Regularly interacts with vendors, regulatory bodies and other external stakeholders exerting influence and negotiating to drive business results
  • Plans and implements the development of new process formulas, establishes operating equipment specifications and improves manufacturing techniques and new process equipment production
  • Acts as liaison with research and/or development to ensure processes and designs are compatible.
  • Selects, develops and evaluates personnel to ensure the efficient operation of the function
  • Supports off-site synthesis and interaction with scale-up/ manufacturing contractors
  • Effectively documents research and conducts work in a safe manner in accordance with company and departmental guidelines
  • Performs other duties as assigned
  • Leads multiple disparate groups and actively contributes to strategic planning for the larger function

Requirements

  • BS/BA degree in Chemistry or similar discipline and 16+ years of experience in pharmaceutical/ process development field and extensive previous leadership experiences also required OR
  • Master's degree in Chemistry or similar discipline and 14+ years of similar experience noted above OR
  • PhD in Chemistry or similar discipline AND 12+ years of similar experience noted above
  • A thorough understanding of organic chemistry and process chemistry as well as current literature is required
  • Manufacturing expertise in Chemical Development
  • Must have a demonstrated track record of managing multiple programs, resources and staff
  • Must have extensive expertise in working with CRO/CMO's both as a lead and a team member
  • Requires in-depth knowledge of the functional area, business strategies, and the company's goals
  • Must be self-motivated, detail-oriented, decisive
  • Ability to quickly learn and think independently

Compensation

  • The annual base salary we reasonably expect to pay is $244,100.00-$333,000.00.

Benefits

  • Drives strategic vision and direction for API Development

Company info

  • Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. ( *in collaboration with AbbVie )
  • At Neurocrine, strong leadership drives both business results and team success. We look for leaders who think strategically, anticipate what's ahead and set clear direction, while building and empowering high-performing teams. Successful leaders foster an environment where people are motivated to do their best work and deliver meaningful, measurable impact through sound decision-making and accountability.
  • Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs.
  • We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders.
  • The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas.
  • For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions.
  • We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science.
  • For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. ( *in collaboration with AbbVie )
  • At Neurocrine, strong leadership drives both business results and team success.
  • We look for leaders who think strategically, anticipate what's ahead and set clear direction, while building and empowering high-performing teams.
  • Successful leaders foster an environment where people are motivated to do their best work and deliver meaningful, measurable impact through sound decision-making and accountability.
  • to relieve suffering for people with great needs.
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