Alumis
Director Clinical Pharmacology & DMPK
South San Francisco · Director
Sponsorship not specifiedDetected 2 days ago
PythonGCPData SciencePharmacologyCommunication
About the role
- Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
- The salary range for this position is $200,000 USD to $240,000 USD annually.
- This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday.
Responsibilities
- Lead clinical pharmacology strategy, dose selection, and PK/PD and biomarker planning across early and late-stage programs.
- Integrate translational and nonclinical PK/PD data to support FIH dose projections and DDI assessments.
- Partner with Clinical Operations on sample management and protocol design.
- Communicate quantitative findings clearly and contribute to regulatory documents (protocols, IBs, INDs, NDAs, IMPDs).
- Collaborate across Clinical Development, Biostats/Data Science, Nonclinical, and Program Management.
- Alumis is seeking a Director of Clinical Pharmacology & DMPK to drive clinical pharmacology strategy and PK/PD modeling for our small-molecule programs in immune-mediated diseases.
- This role partners closely with cross-functional teams and reports to the Head of Clinical Pharmacology & DMPK.
Requirements
- 6 to 8+ years of industry experience in Clinical Pharmacology, DMPK, or Quantitative Pharmacology.
- Strong expertise in PK, PK/PD, DMPK, and translational sciences.
- Proficiency with modeling/simulation platforms (NONMEM, WinNonlin, Simcyp, R, Python).
- Excellent communication, organization, and ability to work independently in a fast-paced environment.
Compensation
- The salary range for this position is $200,000 USD to $240,000 USD annually.
Company info
- Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases.
This listing is sourced directly from Alumis's careers page and normalized into a canonical job model.