Alumis

Alumis

Director Clinical Pharmacology & DMPK

South San Francisco · Director

Sponsorship not specifiedDetected 2 days ago
PythonGCPData SciencePharmacologyCommunication

About the role

  • Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
  • The salary range for this position is $200,000 USD to $240,000 USD annually.
  • This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday.

Responsibilities

  • Lead clinical pharmacology strategy, dose selection, and PK/PD and biomarker planning across early and late-stage programs.
  • Integrate translational and nonclinical PK/PD data to support FIH dose projections and DDI assessments.
  • Partner with Clinical Operations on sample management and protocol design.
  • Communicate quantitative findings clearly and contribute to regulatory documents (protocols, IBs, INDs, NDAs, IMPDs).
  • Collaborate across Clinical Development, Biostats/Data Science, Nonclinical, and Program Management.
  • Alumis is seeking a Director of Clinical Pharmacology & DMPK to drive clinical pharmacology strategy and PK/PD modeling for our small-molecule programs in immune-mediated diseases.
  • This role partners closely with cross-functional teams and reports to the Head of Clinical Pharmacology & DMPK.

Requirements

  • 6 to 8+ years of industry experience in Clinical Pharmacology, DMPK, or Quantitative Pharmacology.
  • Strong expertise in PK, PK/PD, DMPK, and translational sciences.
  • Proficiency with modeling/simulation platforms (NONMEM, WinNonlin, Simcyp, R, Python).
  • Excellent communication, organization, and ability to work independently in a fast-paced environment.

Compensation

  • The salary range for this position is $200,000 USD to $240,000 USD annually.

Company info

  • Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases.

This listing is sourced directly from Alumis's careers page and normalized into a canonical job model.