Personalis, Inc
Sr. Bioinformatics Scientist - Collaborations
Fremont, CA · Senior · Full-time
Stay score
odds of building a lasting career here
Sponsors, but it's cap-subject — you still face the weighted lottery (~61% per draw at Level IV). Good if you win; have a cap-exempt backup on your list.
Lottery odds assume a STEM candidate.
Personalize to your clock →H-1B wage level
the lottery is wage-weighted — each level is one more entry
$17,136 more — $175,136 — moves this role to Level IV and 4 lottery entries. That figure is inside the range the employer already advertised.
Based on the DOL prevailing wage for this occupation and worksite, a base salary of $175,136 would place this position at wage Level IV. That figure is within the posted range, and I'd like to target it. This role classifies under "Biological Scientists, All Other" for prevailing-wage purposes.
DOL prevailing wage, 2026-27 wage year · Biological Scientists, All Other (19-1029) · San Francisco-Oakland-Fremont, CA. Wage level is derived by USCIS from the offered wage, occupation and worksite; the occupation shown is inferred from the job title.
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About the role
- Personalis is based in Fremont, California.
- This position will directly contribute to a new generation of genomics-based precision-medicine products in immuno-oncology, cancer clinical trials, diagnostics, and therapeutics used by pharma, biotech, hospitals, and clinicians.
- The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors.
Responsibilities
- Plan, develop, and manage scientific collaborations, applying internally developed liquid biopsy and solid tumor products to detect somatic variants, neoantigens, and tumor escape mechanisms within high-profile and impactful partnerships
- Build upon our novel cell-free platforms and products, including our NeXT Personal MRD liquid biopsy platform
- Design and execute scientific projects and experiments focused on demonstrating the performance as well as research and clinical advantages our of cell-free platforms
- We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient.
- Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time.
- Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development.
Requirements
- Advanced degree (Ph.D.) in bioinformatics, genomics, or a related field
- Experience managing, analyzing, and interpreting large impactful multi-participant projects
- Experience with cancer liquid biopsy analysis
- Experience with survival analysis
- Proficiency with at least one common programming language (e.g., Python, R)
- Experience with cancer genomics and variant detection
- Experience publishing and presenting scientific results
Compensation
- The hiring range for this position is $158,000 to $190,000 per year, which may factor in various geographic regions.
Company info
- At Personalis, we are transforming the active management of cancer through breakthrough personalized testing.
- As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations.
- Protecting Our Candidates: At Personalis, we value your security.
This listing is sourced directly from Personalis, Inc's careers page and normalized into a canonical job model.